Results 61 to 70 of about 27,628 (212)

Evidence That Cytochrome \u3cem\u3eb\u3csub\u3e5\u3c/sub\u3e\u3c/em\u3e Acts as a Redox Donor in CYP17A1 Mediated Androgen Synthesis [PDF]

open access: yes, 2016
Cytochrome P450 17A1 (CYP17A1) is an important drug target for castration resistant prostate cancer. It is a bi-functional enzyme, catalyzing production of glucocorticoid precursors by hydroxylation of pregnene-nucleus, and androgen biosynthesis by a ...
Denisov, Ilia G.   +5 more
core   +1 more source

Dermoscopy and methyl aminolevulinate: A study for detection and evaluation of field cancerization [PDF]

open access: yes, 2016
Actinic keratosis (AK) is a keratinocyte intraepidermal neoplasia UV light – induced that frequently appears in sun-exposed areas of the skin. Although historically AK was de fi ned as “ precancerous ” , actually it is considered as the ...
Anzalone, Alessia   +9 more
core   +1 more source

Association of iron‐protoporphyrin‐IX (hemin) with myosins [PDF]

open access: yesFEBS Letters, 1990
Addition of myosins isolated from guinea pig heart and rabbit skeletal muscle to hemin solutions resulted in the appearance of new absorption spectra indicating association of hemin and the myosins. Binding stoichiometry based on absorption changes was found to be two hemin sites per myosin molecule.
Bhoite-Solomon, V.   +2 more
openaire   +2 more sources

Long‐Term Control of Human Papillomavirus‐Related Focal Epithelial Hyperplasia in an Human Immunodeficiency Virus‐Positive Patient Using Methylene Blue‐Mediated Photodynamic Therapy. A Case Report

open access: yesLasers in Surgery and Medicine, EarlyView.
ABSTRACT Background Human papillomavirus (HPV) infections are a major cause of oral lesions, and in individuals living with HIV, lesions such as focal epithelial hyperplasia (FEH) may persist or exhibit atypical features, potentially progressing to more severe conditions if untreated.
Juliana Cristina Oliverio de Araújo   +4 more
wiley   +1 more source

5-ALA induced PpIX fluorescence spectroscopy in neurosurgery: a review

open access: yesFrontiers in Neuroscience
The review begins with an overview of the fundamental principles/physics underlying light, fluorescence, and other light-matter interactions in biological tissues.
A. Gautheron   +10 more
doaj   +1 more source

The Molecular Evolution, Structure, and Function of Coproporphyrinogen Oxidase and Protoporphyrinogen Oxidase in Prokaryotes

open access: yesBiology, 2023
Coproporphyrinogen oxidase (CgoX) and protoporphyrinogen oxidase (PgoX) catalyze the oxidation of the flexible cyclic tetrapyrrole of porphyrinogen compounds into fully conjugated, planar macrocyclic porphyrin compounds during heme biosynthesis.
Marcel Zámocký   +3 more
doaj   +1 more source

Role of magnesium in carbon partitioning and alleviating photooxidative damage [PDF]

open access: yes, 2008
Magnesium (Mg) deficiency exerts a major influence on the partitioning of drymatter and carbohydrates between shoots and roots. One of the very early reactions of plants to Mg deficiency stress is themarked increase in the shootto- root dry weight ...
Kirkby, Ernest A., Çakmak, İsmail
core   +1 more source

The continuing significance of chiral agrochemicals

open access: yesPest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Effects of iron deficiency and exogenous sucrose on the intermediates of chlorophyll biosynthesis in Malus halliana.

open access: yesPLoS ONE, 2020
Malus halliana is an iron (Fe)-efficient apple rootstock growing in calcareous soil that shows obvious 'greenness' traits during Fe deficiency. Recent studies have shown that exogenous sugars can be involved in abiotic stress.
Aixia Guo   +5 more
doaj   +1 more source

Immunomodulatory effects of photodynamic therapy for skin cancer: Potential strategies to improve treatment efficacy and tolerability

open access: yesPhotochemistry and Photobiology, EarlyView.
Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio   +4 more
wiley   +1 more source

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