Results 51 to 60 of about 2,261 (129)
The Porphyrins, Origin of Life in Biological Universe and Evolution/Regulation of the Human System [PDF]
, 2012 Objectives: Actinidic archaea have been related to thepathogenesis of schizophrenia, malignancy, metabolicsyndrome x, autoimmune disease and neuronaldegeneration. An actinide dependent shadow biosphere ofarchaea and viroids in the above mentioned disease
Kurup, Parameswara Achutha +1 more
core +2 more sources
The FEBS Journal, EarlyView.Moderate overexpression of wild‐type Met in hepatocytes (Alb‐R26Met mouse model) boosts a strong antioxidant response dependent on the glutathione system while impairing TGF‐β signaling in the liver. This leads to improved liver regeneration and protects against DDC‐induced injury, a model for cholestatic disease sharing features with primary ...
Carlos González‐Corralejo +16 more
wiley +1 more source
Acta Chimica Slovenica, 2014 A high-performance liquid chromatographic analysis for the determination of hemin, protoporphyrin IX (PPIX), and zinc(II)protoporphyrin IX (Zn(II)PPIX) in Parmaham was developed.
Hannelore De Maere +6 more
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Journal of Integrative Plant Biology, EarlyView.Pentatricopeptide repeat proteins coordinate nucleus‐organelle communication by modulating RNA metabolism within chloroplasts and mitochondria. This review highlights how they control critical processes like photosynthesis, seed development, fertility restoration, and stress survival in crops, and explores their potential as programmable tools for RNA ...
Mingming Wu +7 more
wiley +1 more source
Pharmacological versus genetic inhibition of heme oxygenase-1 : the comparison of metalloporphyrins, shRNA and CRISPR/Cas9 system [PDF]
, 2018 Inhibition of heme oxygenase-1 (HO-1, encoded by HMOX1), a cytoprotective, anti-apoptotic and anti-inflammatory enzyme, may serve as a valuable therapy in various pathophysiological processes, including tumorigenesis.
Biela, Anna +9 more
core +1 more source
The Hemoprotein Hhy1 Promotes Heme‐Dependent Catalase Activity of Ctt1
Molecular Microbiology, EarlyView.A Schizosaccharomyces pombe strain deficient in heme (hem1Δ) and siderophore (Fc) biosynthesis, as well as high‐affinity iron (Fe) uptake (blue), was used to uncover the hemoprotein Hhy1 that promotes the heme‐dependent activity of the catalase Ctt1. In contrast, hhy1Δ cells exhibit reduced Ctt1 activity and increased sensitivity to oxidative stress ...
Tobias Vahsen +3 more
wiley +1 more source
Photochemistry and Photobiology, EarlyView.Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio +4 more
wiley +1 more source
On the novel free porphyrins corallistin B, C, D, and E : isolation from the demosponge Corallistes sp. of the Coral Sea and reactivity of their nickel (2) complexes toward formylating reagents [PDF]
, 1993 Reported here are the novel free corallistin B, C, D, and E, isolated as methyl esters 2a, 3a, 4a, and 5a, respectively, from the sponge #Corallistes$ sp.(#Lithistida$) collected at the basis of the South New Caledonian coral reef.
D'Ambrosio, M. +4 more
core
Photochemistry and Photobiology, EarlyView.PFAS are environmental contaminants that induce chemoresistance in ovarian cancer cells. This study evaluated BPD‐PDP or ALA‐PpIX‐PDP in combination with carboplatin or doxorubicin to overcome PFAS‐induced chemoresistance in two cell cohorts: (i) PFAS chronically‐exposed and (ii) PFAS outgrown cells (which underwent a “recovery period” after chronic ...
Brittany P. Rickard +4 more
wiley +1 more source
Metalloprotoporphyrin Inhibition of HCV NS3-4A Protease: Structure–Activity Relationships
Drug Design, Development and Therapy, 2020 Katherine Hu, 1, 2 Zhaowen Zhu, 1, 2 Meleah M Mathahs, 1, 2 Huy Tran, 1, 2 Jerry Bommer, 3, 4 Charles A Testa, 5 Warren N Schmidt 1, 2 1Department of Internal Medicine and Research Service, Veterans Affairs Medical Center, Iowa City, IA 52246, USA ...
Hu K +6 more
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