Results 61 to 70 of about 20,002 (267)

Immunomodulatory effects of photodynamic therapy for skin cancer: Potential strategies to improve treatment efficacy and tolerability

open access: yesPhotochemistry and Photobiology, EarlyView.
Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio   +4 more
wiley   +1 more source

Photodynamic priming (PDP) targets platinum resistance from chronic perfluoroalkyl substances (PFAS) exposure in ovarian cancer cells

open access: yesPhotochemistry and Photobiology, EarlyView.
PFAS are environmental contaminants that induce chemoresistance in ovarian cancer cells. This study evaluated BPD‐PDP or ALA‐PpIX‐PDP in combination with carboplatin or doxorubicin to overcome PFAS‐induced chemoresistance in two cell cohorts: (i) PFAS chronically‐exposed and (ii) PFAS outgrown cells (which underwent a “recovery period” after chronic ...
Brittany P. Rickard   +4 more
wiley   +1 more source

Metalloprotoporphyrin Inhibition of HCV NS3-4A Protease: Structure–Activity Relationships

open access: yesDrug Design, Development and Therapy, 2020
Katherine Hu, 1, 2 Zhaowen Zhu, 1, 2 Meleah M Mathahs, 1, 2 Huy Tran, 1, 2 Jerry Bommer, 3, 4 Charles A Testa, 5 Warren N Schmidt 1, 2 1Department of Internal Medicine and Research Service, Veterans Affairs Medical Center, Iowa City, IA 52246, USA ...
Hu K   +6 more
doaj  

Cell-Free Optimized Production of Protoporphyrin IX [PDF]

open access: gold, 2023
David C. Garcia   +4 more
openalex   +1 more source

Effects of Cobalt and Zinc Stress on Rehmannia glutinosa Growth, Bioactive Compounds, Antioxidant Activity, and Molecular Insights

open access: yesNew Zealand Journal of Crop and Horticultural Science, Volume 54, Issue 1, March 2026.
This study aimed to investigate the effects of cobalt (Co) and zinc (Zn) on the growth, antioxidant activity, total phenolic and flavonoid contents (TPC and TFC), targeted polyphenolic compounds, and molecular dynamics simulations of Rehmannia glutinosa (R. glutinosa) L.
Bimal Kumar Ghimire   +9 more
wiley   +1 more source

Protoporphyrin formation in Rhizobium japonicum [PDF]

open access: yesJournal of Bacteriology, 1983
The obligately aerobic soybean root nodule bacterium Rhizobium japonicum produces large amounts of heme (iron protoporphyrin) only under low oxygen tensions, such as exist in the symbiotic root nodule. Aerobically incubated suspensions of both laboratory-cultured and symbiotic bacteria (bacteroids) metabolize delta-aminolevulinic acid to uroporphyrin ...
J H, Keithly, K D, Nadler
openaire   +2 more sources

Increased Porphyrins in Primary Liver Cancer Mainly Reflect a Parallel Liver Disease [PDF]

open access: yes, 2009
Hepatic porphyries have been associated with an increased risk of primary liver cancer (PLC), which on the other hand may cause an increased porphyrin production.
Hansson, Göran   +2 more
core   +3 more sources

The porphyrin ring rather than the metal ion dictates long-range electron transport across proteins suggesting coherence-assisted mechanism.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
The fundamental biological process of electron transfer (ET) takes place across proteins with common ET pathways of several nanometers. Recent discoveries push this limit and show long-range extracellular ET over several micrometers.
Y. Agam   +4 more
semanticscholar   +1 more source

Emerging 2D Materials and Their Hybrid Nanostructures for Label‐Free Optical Biosensing: Recent Progress and Outlook

open access: yesAdvanced Functional Materials, Volume 36, Issue 11, 5 February 2026.
This review highlights recent advances in label‐free optical biosensors based on 2D materials and rationally designed mixed‐dimensional nanohybrids, emphasizing their synergistic effects and novel functionalities. It also discusses multifunctional sensing platforms and the integration of machine learning for intelligent data analysis.
Xinyi Li, Yonghao Fu, Yuehe Lin, Dan Du
wiley   +1 more source

On the novel free porphyrins corallistin B, C, D, and E : isolation from the demosponge Corallistes sp. of the Coral Sea and reactivity of their nickel (2) complexes toward formylating reagents [PDF]

open access: yes, 1993
Reported here are the novel free corallistin B, C, D, and E, isolated as methyl esters 2a, 3a, 4a, and 5a, respectively, from the sponge #Corallistes$ sp.(#Lithistida$) collected at the basis of the South New Caledonian coral reef.
D'Ambrosio, M.   +4 more
core  

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