Results 31 to 40 of about 610,579 (177)

Indenyl-thiazole and indenyl-formazan derivatives: Synthesis, anticancer screening studies, molecular-docking, and pharmacokinetic/ molin-spiration properties

PLoS ONE, 2023
Two new series of thiazole and formazan linked to 5-Bromo-indan were synthesized, and their structures were assured based on all possible analytical techniques.
Ghaidaa H. Alfaifi, Thoraya A. Farghaly, Magda H. Abdellattif   +2 more
doaj   +2 more sources

Fomesafen absorption site as a mechanism of resistance in an Euphorbia heterophylla biotype resistant to PROTOX inhibitors [PDF]

, 2009
Três experimentos foram realizados para verificar se o local de aplicação de fomesafen, folhas ou solo, afeta a eficácia desse herbicida em biótipos de E.
Vidal, Ribas Antonio, Silva, Rafael Pedroso da, Gustmann, Mara Stoco, Kruse, Nelson Diehl, Franchin, Edson, Trezzi, Michelangelo Muzell   +5 more
core   +1 more source

Interação entre inseticida organofosforado e herbicidas inibidores da protox e sua implicação na resistência de Euphorbia heterophylla [PDF]

, 2009
A metabolização dos herbicidas é um dos mecanismos que conferem resistência aos herbicidas em plantas daninhas. Inseticidas organofosforados inibem as enzimas que são responsáveis pela metabolização de herbicidas.
TREZZI, Michelangelo Muzell, PORTES, Emerson da Silva, Silva Portes, Emerson da, Nunes, Anderson Luis, Muzell Trezzi, Michelangelo   +4 more
core   +1 more source

Efeito da compactação do solo e do sulfentrazone sobre a cultura da soja em duas condições de água no solo Effect of soil compaction and sulfentrazone on soybean under two soil moisture conditions

Planta Daninha, 2007
Estudou-se neste trabalho a atividade do sulfentrazone sobre plantas de soja cultivadas em um Latossolo Vermelho distroférrico com diferentes níveis de compactação.
L.H.S. Zobiole, R.S. Oliveira Jr., C.A. Tormena, J. Constantin, S.D. Cavalieri, D.G. Alonso, A.M. Brighenti, C. Castro   +7 more
doaj   +1 more source

Novel bi- and trifunctional inhibitors of tumor-associated proteolytic systems [PDF]

, 2003
Serine proteases, cysteine proteases, and matrix metalloproteinases (MMPs) are involved in cancer cell invasion and metastasis. Recently, a recombinant bifunctional inhibitor (chCysuPA(19-31)) directed against cysteine proteases and the urokinasetype ...
Sato, Sumito, Assfalg-Machleidt, Irmgard, Magdolen, Ulla, Schmitt, Manfred, Rettenberger, Peter, Magdolen, Viktor, Krol, Janna   +6 more
core   +1 more source

Resistência de amendoim-bravo aos herbicidas inibidores da enzima acetolactato sintase Wild poinsettia resistance to acetolactate synthase inhibitor herbicides

Planta Daninha, 1999
O controle contínuo de plantas daninhas através da aplicação de herbicidas que apresentam atividade em um único local de ação nas plantas favorece a seleção de biótipos resistentes a estes herbicidas, em certas espécies vegetais.
Ribas A. Vidal, Aldo Merotto Jr.
doaj   +1 more source

Computational drug repurposing of Akt-1 allosteric inhibitors for non-small cell lung cancer

Scientific Reports, 2023
Non-small cell lung carcinomas (NSCLC) are the predominant form of lung malignancy and the reason for the highest number of cancer-related deaths. Widespread deregulation of Akt, a serine/threonine kinase, has been reported in NSCLC.
Krishnaprasad Baby, Swastika Maity, Chetan Hasmukh Mehta, Usha Y. Nayak, Gautham G. Shenoy, Karkala Sreedhara Ranganath Pai, Kuzhuvelil B. Harikumar, Yogendra Nayak   +7 more
doaj   +1 more source

DHFR-inhibitors

, 2022
Archive of DHFR-inhibitors containing sub-folders named after each compound and its net charge. Every compound's folder contains a total of 20 files distributed into three sub-directories reporting QM (QM/), FF (FF/), and MD (MD ...
Giuliano Malloci (2060875), Silvia Gervasoni (6169202), Andrea Bosin (6743129), Helen I. Zgurskaya (3093648), Attilio Vittorio Vargiu (2358538), Paolo Ruggerone (247673)   +5 more
core   +1 more source

ProtoX: A First Look

, 2023
We present a first look at ProtoX, a code generation framework for stencil and pointwise operations that occur frequently in the numerical solution of partial differential equations.
Mankad, Het, Van Straalen, Brian, Franchetti, Franz, Colella, Phillip, Rao, Sanil   +4 more
core  

High Throughput Screens Yield Small Molecule Inhibitors of Leishmania CRK3:CYC6 Cyclin-Dependent Kinase [PDF]

, 2011
Background: Leishmania species are parasitic protozoa that have a tightly controlled cell cycle, regulated by cyclin-dependent kinases (CDKs). Cdc2-related kinase 3 (CRK3), an essential CDK in Leishmania and functional orthologue of human CDK1, can form ...
Walker, Roderick G., Brown, Elaine, Thomson, Graeme, Blake, David G., Malone, Kirk, Turner, Nicholas J., Grant, Karen, Mottram, Jeremy C., Walkinshaw, Malcolm D., Nowicki, Matthew W.   +9 more
core   +3 more sources