Results 1 to 10 of about 176,158 (249)

Depletion of Toxoplasma adenine nucleotide translocator leads to defects in mitochondrial morphology

Parasites & Vectors, 2022
Background Adenine nucleotide translocase (ANT) is a protein that catalyzes the exchange of ADP/ATP across the inner mitochondrial membrane. Beyond this, ANT is closely associated with cell death pathways and mitochondrial dysfunction.
Yihan Wu, Zhu Ying, Jing Liu, Zhepeng Sun, Shuang Li, Qun Liu   +5 more
doaj   +1 more source

Establishment of Recombinant Eimeria acervulina Expressing Multi-Copies M2e Derived from Avian Influenza Virus H9N2

Vaccines, 2021
The potential of Eimeria parasites as live vaccine vectors has been reported with successful genetic manipulation on several species like E. tenella, E. mitis and E. necatrix. Among seven Eimeria species infecting chickens, E.
Sixin Zhang, Xinming Tang, Si Wang, Fangyun Shi, Chunhui Duan, Feifei Bi, Jingxia Suo, Dandan Hu, Jie Liu, Chaoyue Wang, Xun Suo, Xianyong Liu   +11 more
doaj   +1 more source

Microneme Protein 6 Is Involved in Invasion and Egress by Neospora caninum

Pathogens, 2021
Background: Neospora caninum, is the etiological agent of neosporosis, an infection that causes abortions in cattle and nervous system dysfunction in dogs. Invasion and egress are the key steps of the pathogenesis of N. caninum infection.
Xianmei Wang, Di Tang, Fei Wang, Gaowei Jin, Lifang Wang, Qun Liu, Jing Liu   +6 more
doaj   +1 more source

Requirement of Toxoplasma gondii metacaspases for IMC1 maturation, endodyogeny and virulence in mice

Parasites & Vectors, 2021
Background Metacaspases are multifunctional proteins found in plants, fungi and protozoa, and are involved in processes such as insoluble protein aggregate clearance and cell proliferation.
Muzi Li, Jing Liu, Yayun Wu, Yihan Wu, Xiaodong Sun, Yong Fu, Xiao Zhang, Qun Liu   +7 more
doaj   +1 more source

Transcriptomic and metabolomic analyses reveal the essential nature of Rab1B in Toxoplasma gondii

Parasites & Vectors, 2023
Background The protozoan parasite Toxoplasma gondii encodes a dozen Rab proteins, which are parts of the small GTPase superfamily and regulate intracellular membrane trafficking.
Kai He, Qiangqiang Wang, Xuwen Gao, Tao Tang, Huiyong Ding, Shaojun Long   +5 more
doaj   +1 more source

Functional characterization of acyl-CoA binding protein in Neospora caninum

Parasites & Vectors, 2020
Background Lipid metabolism is pivotal for the growth of apicomplexan parasites. Lipid synthesis requires bulk carbon skeleton acyl-CoAs, the transport of which depends on the acyl-CoA binding protein (ACBP).
Bingxin Zhou, Yong Fu, Heng Zhang, Xianmei Wang, Gaowei Jin, Jianhai Xu, Qun Liu, Jing Liu   +7 more
doaj   +1 more source

Biotinylation of the Neospora caninum parasitophorous vacuole reveals novel dense granule proteins

Parasites & Vectors, 2021
Background Neospora caninum is an obligate intracellular parasite that invades host cells and replicates within the parasitophorous vacuole (PV), which resists fusion with host cell lysosomal compartments. To modify the PV, the parasite secretes an array
Congshan Yang, Chenrong Wang, Jing Liu, Qun Liu   +3 more
doaj   +1 more source

Deletion of Toxoplasma Rhoptry Protein 38 (PruΔrop38) as a Vaccine Candidate for Toxoplasmosis in a Murine Model

Biomedicines, 2022
Toxoplasmosis is a serious zoonotic disease that threatens human and animal health. Here, we evaluated the vaccine potential of the deletion of Toxoplasma rhoptry protein 38 (PruΔrop38) through its pathogenicity and immunoprotective efficacy in mice ...
Yayun Wu, Zihui Zhou, Zhu Ying, Ying Xu, Jing Liu, Qun Liu   +5 more
doaj   +1 more source

The Occurrence and Meta-Analysis of Investigations on Sarcocystis Infection among Ruminants (Ruminantia) in Mainland China

Animals, 2022
Sarcocystis is a zoonotic pathogen that threatens public health and the quality of food safety. To determine the Sarcocystis spp. prevalence in ruminants (Ruminantia) in China, we conducted a systematic review and meta-analysis.
Zifu Zhu, Zhu Ying, Zixuan Feng, Qun Liu, Jing Liu   +4 more
doaj   +1 more source

Molecular detection and identification of three intracellular parasites of retail mutton products in Beijing, China

Frontiers in Veterinary Science, 2022
Sarcocystis spp., Neospora caninum and Toxoplasma gondii are globally ubiquitous pathogens, and domestic sheep are considered to be one of the intermediate hosts.
Zifu Zhu, Yajie Chen, Xu Yang, Lifang Wang, Qun Liu, Qun Liu, Jing Liu, Jing Liu   +7 more
doaj   +1 more source