Results 141 to 150 of about 92,683 (284)
Neutrophil Extracellular Traps in Atherosclerosis and Cardiovascular Disease
NETs as integrated effectors in the atherosclerotic cardiovascular disease continuum. Activated neutrophils release NETs that promote endothelial injury, thrombo‐inflammation, and plaque destabilization throughout atherosclerotic disease progression. Created with BioRender.com.
Ji Zhang +9 more
wiley +1 more source
Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva +10 more
wiley +1 more source
ABSTRACT Introduction Neotropical primates (NTPs) present varying susceptibility to toxoplasmosis caused by Toxoplasma gondii, but their immunopathogenic responses remain poorly understood. Materials and Methods Local immune responses were characterized in the liver, spleen, and central nervous system (CNS) of 50 naturally infected NTPs (31 Callithrix ...
Marina Pellegrino +9 more
wiley +1 more source
Spontaneous Hepatobiliary Disease in a Breeding Colony of Aotus spp.
ABSTRACT Background Owl monkeys are nonhuman primate species in the genus Aotus. The Michale E. Keeling Center for Comparative Medicine and Research maintains an Owl Monkey Breeding and Research Resource composed of four species of owl monkeys: Aotus nancymai, A. vociferans, A. azarae, and A. griseimembra.
M. E. Hensel +4 more
wiley +1 more source
Detection of Water Borne Protozoa
Protozoa of several species play a key role in water borne outbreaks of diarrhea worldwide. Identification of such protozoa depends mainly on parasite detection.
Al-Sabi, Mohammad Nafi Solaiman +2 more
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Host–Microbe Mechanisms of Fusobacterium nucleatum in Colorectal Cancer
Fusobacterium nucleatum and colorectal cancer. ABSTRACT The oral‐derived pathobiont Fusobacterium nucleatum has increasingly been implicated in colorectal cancer (CRC) progression through its ability to modulate inflammatory, immunological, and molecular pathways. F.
Hadda Lyzandra Austríaco Leite +1 more
wiley +1 more source
Transcriptomic and metabolomic profiling of Ornithodoros lahorensis during African swine fever virus (ASFV) infection reveals that ASFV rewires host purine/pyrimidine metabolism, lipid metabolism, and energy metabolism. A core gene‐metabolite regulatory axis consisting of 12 key genes and 8 signature metabolites is identified to support viral genome ...
Jin Luo +9 more
wiley +1 more source

