Results 81 to 90 of about 100,965 (319)

Co-immunization with two recombinant Eimeria tenella lines expressing immunoprotective antigens of E. maxima elicits enhanced protection against E. maxima infection

Parasites & Vectors, 2019
Background Live anticoccidial vaccines have been a tremendous success for disease prevention. The establishment of the reverse genetic manipulation platform has enabled the development of Eimeria parasites, the live anticoccidial vaccine strains, as ...
Xinming Tang, Chaoyue Wang, Lin Liang, Dandan Hu, Sixin Zhang, Chunhui Duan, Jingxia Suo, Xianyong Liu, Xun Suo, Shangjin Cui   +9 more
doaj   +1 more source

Antileishmanial Activities of Carvacrol Nanoencapsulate in Biopolymeric Nanoparticles

Chemistry &Biodiversity, EarlyView.
The study obtained biopolymeric nanoparticles containing carvacrol (NPCar) and evaluated their anti‐leishmanial activity. NPCar obtained presented physicochemical characteristics due to its ideal nanometric size and zeta potential, and low polydispersity index.
Joyce Cordeiro Borges, Anne Beatriz Cunha Barros, Leonardo Lima Cardoso, Tatjana de Lima Souza Keesen, Luís André de Almeida Campos, Isabella Macário Ferro Cavalcanti, Elisângela Afonso de Moura Kretzschmar   +6 more
wiley   +1 more source

Molecular characterization and zoonotic potential of Entamoeba spp., Enterocytozoon bieneusi and Blastocystis from captive wild animals in northwest China

BMC Veterinary Research
Background Parasites Entamoeba spp., Enterocytozoon bieneusi and Blastocystis are prevalent pathogens causing gastrointestinal illnesses in animals and humans.
Yuexin Wang, Yuechen Zeng, Yaoli Wu, Furui Lu, Xiaopeng Hou, Junfeng Shao, Tengteng Zhang, Chen Shao   +7 more
doaj   +1 more source

Efficient Single-Gene and Gene Family Editing in the Apicomplexan Parasite Eimeria tenella Using CRISPR-Cas9

Frontiers in Bioengineering and Biotechnology, 2020
Eimeria species are pathogenic protozoa with a wide range of hosts and the cause of poultry coccidiosis, which results in huge economic losses to the poultry industry.
Dandan Hu, Xinming Tang, Choukri Ben Mamoun, Chaoyue Wang, Si Wang, Xiaolong Gu, Chunhui Duan, Sixin Zhang, Jinxia Suo, Miner Deng, Yonglan Yu, Xun Suo, Xianyong Liu   +12 more
doaj   +1 more source

A Simple and Efficient Stereoselective Synthesis of a 2,3‐Difluorosialic Acid‐Based Influenza Virus Neuraminidase Inhibitor

Chemistry – A European Journal, Volume 31, Issue 16, March 17, 2025.
A new simple approach for the exquisitely stereo‐controlled introduction of the C‐3 equatorial fluorine on neuraminic acid derivatives by incorporation of steric bulk at C‐4. Through this size‐controlled method, we have elaborated a novel synthetic route that exclusively produces the potent anti‐influenza drug candidate; 2,3‐difluoro‐zanamivir analogue
Ibrahim M. El‐Deeb, Mark von Itzstein
wiley   +1 more source

Potential role of bacteria packaging by protozoa in the persistence and transmission of pathogenic bacteria

Frontiers in Microbiology, 2014
Many pathogenic bacteria live in close association with protozoa. These unicellular eukaryotic microorganisms are ubiquitous in various environments. A number of protozoa such as amoebae and ciliates ingest pathogenic bacteria, package them usually in ...
A. Denoncourt, V. Paquet, S. Charette
semanticscholar   +1 more source

Efficient and Rapid Arylation of NH₂‐Unprotected Bromobisindole Ethanamines via Suzuki‐Miyaura Coupling: Generating New Leads Against Leishmania

Chemistry – A European Journal, EarlyView.
A library of novel bisindole derivatives was synthesized through an optimized rapid Suzuki‐Miyaura coupling reaction, utilizing NH2‐unprotected bromobisindole ethanamines and boronic acids with yields up to 93%. The compounds were screened for their activity against L. infantum promastigotes.
Alessandro Buono, Aurora Diotallevi, Sara Maestrini, Michele Verboni, Paula Kiuru, Luca Galluzzi, Andrea Duranti, Diego Olivieri, Simone Lucarini   +8 more
wiley   +1 more source

The genome sequence of the Heterolobosean amoeboflagellate, Tetramitus jugosus CCAP 1588/3C [version 1; peer review: 2 approved]

Wellcome Open Research, 2023
We present a genome assembly from cultivated Tetramitus jugosus (Heterolobosea; Schizopyrenida; Vahlkampfiidae). The genome sequence is 26.3 megabases in span. Most of the assembly (99.3%) is scaffolded into 52 chromosomal pseudomolecules.
Cecilia Rad-Menéndez, David H. Green
doaj  

Programmed Cell Death Ligand (PD-L)-1 Contributes to the Regulation of CD4+ T Effector and Regulatory T Cells in Cutaneous Leishmaniasis

Frontiers in Immunology, 2020
Cutaneous Leishmaniasis (CL) affects up to one million people every year and treatments are costly and toxic. The regulation of the host immune response is complex and the knowledge of how CD4+ T cells are activated and maintained during Leishmania ...
Rafael de Freitas e Silva, Rafael de Freitas e Silva, Rosa Isela Gálvez, Valéria Rego Alves Pereira, Maria Edileuza Felinto de Brito, Siew Ling Choy, Hannelore Lotter, Lidia Bosurgi, Lidia Bosurgi, Thomas Jacobs   +9 more
doaj   +1 more source

Artificial Protozoa Optimizer (APO): A novel bio-inspired metaheuristic algorithm for engineering optimization [PDF]

This study proposes a novel artificial protozoa optimizer (APO) that is inspired by protozoa in nature. The APO mimics the survival mechanisms of protozoa by simulating their foraging, dormancy, and reproductive behaviors. The APO was mathematically modeled and implemented to perform the optimization processes of metaheuristic algorithms.
arxiv   +1 more source