Results 81 to 90 of about 58,787 (233)
The role of T cells in sepsis of distinct infectious aetiologies
Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.Pathogen‐specific sepsis induces mitochondrial dysfunction in T cells, leading to functional alterations. Single‐cell transcriptomics reveals subtype‐specific impairments involving reactive oxygen species accumulation, mtDNA damage, calcium dysregulation, and metabolic reprogramming.
Xuanqi Liu +5 more
wiley +1 more source
SwarmGenomics: A Unified Pipeline for Individual‐Based Whole‐Genome Analyses
Molecular Ecology Resources, Volume 26, Issue 3, April 2026.ABSTRACT Advances in sequencing technologies have made whole‐genome data widely accessible, enabling research in population genetics, evolutionary biology, and conservation. However, analysing whole‐genome sequencing (WGS) data remains challenging, often requiring multiple specialised tools and substantial bioinformatics expertise.
Aure Kylmänen +5 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 6, 31 March 2026.Effects of PEPCK deficiency in Trypanosoma cruzi bioenergetics and life stages. ABSTRACT Trypanosoma cruzi, the causative agent of Chagas disease, possesses glycosomes—unique organelles that house key metabolic enzymes, several of which are promising therapeutic targets.
Carolina S. D. Vieira +8 more
wiley +1 more source
Antimicrobial and Cytotoxic Activities of Biogenic Nanoparticles Produced by Cyanobacteria
ChemBioChem, Volume 27, Issue 5, 13 March 2026.The article reviews the green synthesis of biogenic nanoparticles produced by cyanobacteria, highlighting their antimicrobial and cytotoxic properties. These nanoparticles, formed intra‐ or extracellularly, show activity against Gram‐positive and Gram‐negative bacteria as well as fungi and can induce apoptosis in tumor cells.
Laíne Santos Ribeiro +4 more
wiley +1 more source
Epidemiology and Molecular Characterization of Entamoeba spp. in Non-Human Primates in Zoos in China
Veterinary SciencesThe genus Entamoeba infects both humans and NHPs. In zoos, visitors feeding significantly increases the frequency of human-to-NHP contact, thereby raising the risk of zoonotic transmission.
Diya An +5 more
doaj +1 more source
Quinic Acid and Synthetic Derivatives in Medicinal Chemistry
ChemMedChem, Volume 21, Issue 5, 13 March 2026.Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel +2 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, Volume 600, Issue 5, Page 591-611, March 2026.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Archiv der Pharmazie, Volume 359, Issue 3, March 2026.Chromone‐based derivatives were synthesized and evaluated for selective inhibition of tumor‐associated carbonic anhydrases IX and XII. Structure–activity relationships, docking studies, and ADMET profiling revealed promising candidates with selective tumoral isoform inhibition, supporting their potential as anticancer leads. ABSTRACT A small library of
Lisa Sequeira +13 more
wiley +1 more source
Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.Ethanolic extracts from leaves, stems, and roots of Schinus weinmanniifolia Mart. ex Engl. were evaluated for phytochemical composition and biological activities. The extracts exhibited antioxidant, photoprotective, and antimicrobial activity, without hemolytic effects or cytotoxicity at active concentrations. Syringic acid, epicatechin, and rutin were
João Andrade +14 more
wiley +1 more source
Protozoan-based biodiversity-safeguarding benchmark for triclosan in freshwater ecosystems
Ecotoxicology and Environmental SafetyThe global usage of triclosan (TCS)-containing disinfectants posed toxicity threats to freshwater biodiversity; at the same time, the ecological risk assessments based on Species Sensitivity Distribution (SSD) models overestimated the Predicted No-Effect
Kexin Yu +9 more
doaj +1 more source