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Intracellular Ca2+ Signaling in Protozoan Parasites: An Overview with a Focus on Mitochondria
International Journal of Molecular Sciences, 2021 Ca2+ signaling has been involved in controling critical cellular functions such as activation of proteases, cell death, and cell cycle control. The endoplasmatic reticulum plays a significant role in Ca2+ storage inside the cell, but mitochondria have ...
Célia Regina da Silva Garcia
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Expert Review of Proteomics, 2009
Protozoan parasites are a major threat to human health with millions of fatalities worldwide, especially in nonindustrialized countries. Currently, there is no cure for many of these parasitic diseases. Consequently, there is an imperative to find treatment targets and develop novel drugs based on the proteins encoded in the genomes of these parasites.
Ahmed, Fadiel +5 more
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Protozoan parasites are a major threat to human health with millions of fatalities worldwide, especially in nonindustrialized countries. Currently, there is no cure for many of these parasitic diseases. Consequently, there is an imperative to find treatment targets and develop novel drugs based on the proteins encoded in the genomes of these parasites.
Ahmed, Fadiel +5 more
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International Journal of Food Microbiology, 2005
This report addresses Cryptosporidium, Giardia, Cyclospora, and more briefly, Toxoplasma as the main parasitic protozoa of concern to food production worldwide. Other parasitic protozoa may be spread in food or water but are not considered as great a risk to food manufacture.
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This report addresses Cryptosporidium, Giardia, Cyclospora, and more briefly, Toxoplasma as the main parasitic protozoa of concern to food production worldwide. Other parasitic protozoa may be spread in food or water but are not considered as great a risk to food manufacture.
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Frontiers in Bioscience, 2001
Studies on host-pathogen interactions have led to the discovery of various cell surface associated and secretory molecules. Mucins and mucin-like molecules have recently been described in several protozoan parasites, at different stages of the life cycle.
M, Jain +3 more
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Studies on host-pathogen interactions have led to the discovery of various cell surface associated and secretory molecules. Mucins and mucin-like molecules have recently been described in several protozoan parasites, at different stages of the life cycle.
M, Jain +3 more
openaire +3 more sources
Pediatrics In Review, 2016
• Stool antigen detection for Cryptosporidium sp, Giardia lamblia and Entamoeba histolytica are now commercially available, have better sensitivity and specificity than the traditional stool microscopy, and are less dependent on personnel skill.
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• Stool antigen detection for Cryptosporidium sp, Giardia lamblia and Entamoeba histolytica are now commercially available, have better sensitivity and specificity than the traditional stool microscopy, and are less dependent on personnel skill.
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The glyoxalase pathway in protozoan parasites
International Journal of Medical Microbiology, 2012 The glyoxalase system is the main catabolic route for methylglyoxal, a non-enzymatic glycolytic byproduct with toxic and mutagenic effects. This pathway includes two enzymes, glyoxalase I and glyoxalase II, which convert methylglyoxal to d-lactate by using glutathione as a catalytic cofactor.
Carlos Cordeiro +2 more
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The Topoisomerases of Protozoan Parasites
Parasitology Today, 2000Protozoan parasites are responsible for a wide range of debilitating and fatal diseases that are proving notoriously difficult to treat. Many of the standard chemotherapies in use today are expensive, have toxic side effects and, in some cases have marginal efficacy because of the emergence of drug-resistant parasites.
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Update on protozoan parasites of the intestine
Current Opinion in Gastroenterology, 2002The last year has seen new approaches to the diagnosis, treatment, and prevention of protozoal infections of the gastrointestinal tract. Some of the news is not good: new foodborne and swimming pool outbreaks of cyclosporiasis and cryptosporidiosis, respectively, occurred in North America; paromomycin was shown to be ineffective treatment for ...
Andrea N, Davis +2 more
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Calcium regulation in protozoan parasites
Current Opinion in Microbiology, 2003The calcium ion (Ca(2+)) is used as a major signaling molecule in a diverse range of eukaryotic cells including several human parasitic protozoa, such as Trypanosoma cruzi, Trypanosoma brucei, Leishmania spp, Plasmodium spp, Toxoplasma gondii, Cryptosporidium parvum, Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis.
Silvia N J, Moreno, Roberto, Docampo
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2008
Transmission of infectious agents by blood transfusion has been an ongoing concern of transfusion medicine for decades. For years, the focus of concern has appropriately been on a variety of viral agents (e.g. HIV, hepatitis viruses, West Nile virus) that are known to pose blood safety risks.
David A. Leiby, Silvano Wendel
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Transmission of infectious agents by blood transfusion has been an ongoing concern of transfusion medicine for decades. For years, the focus of concern has appropriately been on a variety of viral agents (e.g. HIV, hepatitis viruses, West Nile virus) that are known to pose blood safety risks.
David A. Leiby, Silvano Wendel
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