Results 111 to 120 of about 45,570 (245)

Advances in high‐resolution cryo‐volume electron microscopy (cvEM) imaging for unicellular and multicellular organisms

Journal of Microscopy, EarlyView.
Abstract Cryo‐Focused Ion Beam Scanning Electron Microscopy (cryoFIB‐SEM) using samples fixed by high‐pressure freezing uniquely enables high‐resolution cryo‐volume Electron Microscope (cvEM) images of cell ultrastructure to be obtained from whole cells and complex tissues in their near native state. As the freezing process also preserves fluorescence,
Maryna Kobylynska, Daniel Nicholls, Zoe Broad, Jack Wells, Alex Robinson, Stefania Marcotti, Damien McGrouther, Ch'ng Q‐L, Genoveva Esteban, Nigel Browning, Roland Fleck   +10 more
wiley   +1 more source

Pharmacokinetics of Diclazuril in the Plasma and Cerebrospinal Fluid of Healthy Adult Horses After a Single Oral Dose Administered as a Pelleted Topdressing

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Equine protozoal myeloencephalitis can cause acute infections with rapid onset of neurologic signs, necessitating immediate empiric therapy with antiprotozoal medication. The objective of the study was to identify when concentrations of diclazuril reached the MIC of Sarcocystis neurona in CSF (1 ng/mL) of healthy adult horses after a single ...
Elizabeth J. Treece, Kate L. Hepworth‐Warren, Mark G. Papich, Philip D. van Harreveld, Anthony T. Blikslager, Faith E. Church, Kaitlyn B. Harbor, Sara J. Erwin‐Craig   +7 more
wiley   +1 more source

Identification of TgCBAP, a novel cytoskeletal protein that localizes to three distinct subcompartments of the toxoplasma gondii pellicle

, 2014
This work was supported by US Public Health Service grant AI054961 (GEW).The cytoskeletons of Toxoplasma gondii and related apicomplexan parasites are highly polarized, with apical and basal regions comprised of distinct protein complexes.
Lucas D Tilley, Shruthi Krishnamurthy (571344), Nicholas J. Westwood (254891), Shruthi Krishnamurthy, Gary E. Ward (208054), Tilley, Lucas D., Lucas D. Tilley (208044), Nicholas J Westwood, Krishnamurthy, Shruthi, Gary E Ward, Westwood, Nicholas J., Ward, Gary E.   +11 more
core   +1 more source

Table_4_Proteomic analysis of Atg8-dependent recruitment of phagosomal proteins in the enteric protozoan parasite Entamoeba histolytica.xlsx

, 2022
Autophagy is one of the bulk degradation systems and is conserved throughout eukaryotes. In the enteric protozoan parasite Entamoeba histolytica, the causative agent of human amebiasis, Atg8 is not exclusively involved in autophagy per se but also in ...
Natsuki Watanabe (5120135), Ratna Wahyuni (13898442), Kumiko Shibata (13898439), Eri Miyamoto (13898445), Tomoyoshi Nozaki (131314), Kumiko Nakada-Tsukui (181460)   +5 more
core   +1 more source

Turnip mosaic virus utilizes the lipid droplet biogenesis machinery to facilitate its propagation in plants

New Phytologist, EarlyView.
Potyvirus turnip mosaic virus induces neutral lipid accumulation and lipid droplet biogenesis in infected leaves for its own benefit. Summary Lipid droplets (LDs), which are dedicated to storing neutral lipids (NLs), are dynamic organelles involved in numerous other functions, including membrane remodeling during abiotic stress.
Léna Jambou, Nathalie Arvy, Marguerite Batsale, Luc Sofer, Sara Shakir, Marielle Cochet, Vincent Simon, Charlotte Quinteau, Thomas Scotti, Nathan M. Doner, Satinder K. Gidda, Robert T. Mullen, Sabine D'Andréa, Jean‐Luc Gallois, Denis Coulon, Claire Bréhélin, Sylvie German‐Retana   +16 more
wiley   +1 more source

Validation of mitochondrial localization and essentiality of prioritized proteins assigned to the tripartite attachment complex in the protozoan parasite Trypanosoma brucei

, 2022
During this thesis the localization of the prioritized proteins Tb927.11.13600, Tb927.11.14570, Tb927.4.840 and Tb927.6.4540 and their connection to the tripartite attachment complex of the protozoan parasite Trypanosoma brucei was examined to verify ...
BITTNER, Jacqueline
core  

Table_1_Proteomic analysis of Atg8-dependent recruitment of phagosomal proteins in the enteric protozoan parasite Entamoeba histolytica.xlsx

, 2022
Autophagy is one of the bulk degradation systems and is conserved throughout eukaryotes. In the enteric protozoan parasite Entamoeba histolytica, the causative agent of human amebiasis, Atg8 is not exclusively involved in autophagy per se but also in ...
Natsuki Watanabe (5120135), Ratna Wahyuni (13898442), Kumiko Shibata (13898439), Eri Miyamoto (13898445), Tomoyoshi Nozaki (131314), Kumiko Nakada-Tsukui (181460)   +5 more
core   +1 more source

The past, present and future of fluorescent protein tags in anaerobic protozoan parasites

Parasitology, 2015
SUMMARYThe world health organization currently recognizes diarrhoeal diseases as a significant cause of death in children globally. Protozoan parasites such asGiardiaandEntamoebathat thrive in the oxygen-deprived environment of the human gut are common etiological agents of diarrhoea.
Victoria, Morin-Adeline, Jan, Šlapeta
openaire   +2 more sources

Selenium‐Containing 1,4‐Naphthoquinone Derivatives Trigger Reactive Oxygen Species and Apoptosis in Triple‐Negative Breast Cancer Cells

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Cancer ranks as a leading cause of death worldwide, demanding new affordable therapies. Nature offers a diverse array of bioactive scaffolds, including 1,4‐naphthoquinone, which serves as a precursor for numerous natural and synthetic compounds with potent antitumor properties.
Eduardo Angulo‐Elizari, Asif Raza, Hannah Johnson, Nuria Martínez‐Sáez, Ignacio Encío, Arun K. Sharma, Carmen Sanmartín, Daniel Plano   +7 more
wiley   +1 more source

Comparative proteomics of Giardia duodenalis from humans and cattle

, 2012
Giardia duodenalis is a gastrointestinal parasite capable of infecting humans as well domesticated animals, for example cattle. There are seven distinct genetic groups, termed assemblages A-G, with assemblages A and B able to infect humans and assemblage
Steuart, Robert
core