Results 121 to 130 of about 45,570 (245)
Unusual MRI features in a case of presumed canine tick‐borne meningoencephalomyelitis
Abstract A 7‐year‐old, standard, wire‐haired dachshund presented with quickly progressive multifocal central nervous system signs, which localised to the brainstem and cervical myelopathy, including reduced cervical and thoracic limb muscle tone and withdrawal reflexes. Magnetic resonance imaging revealed bilateral, approximately symmetric, T2‐weighted
Jon Prager +2 more
wiley +1 more source
RHOPTRY PROTEINS OF PLASMODIUM SPECIES
Rhoptry proteins of Plasmodium sp. participate in host cell invasion and intracellular parasite development. In this review, the major rhoptry proteins of P.
Sam-Yellowe, Tobiliy +3 more
core
Protein synthesis in mitochondria isolated from the trypanosomatid protozoan Crithidia fasciculata [PDF]
Evidence presented over the years in support of mitochondrial translation in trypanosomes, based largely on studies using differential inhibitors such as cycloheximide and chloramphenicol, remains controversial. I have studied endogenous mRNA‐dependent translation in a mitochondrial fraction isolated from the trypanosomatid protozoan Crithidia ...
openaire +2 more sources
Mass spectrometry proteomics for studying mitostasis
Abstract Maintaining mitochondrial integrity and function is fundamental to cellular homeostasis. Cells rely on coordinated protein quality control (QC) systems—including intricate chaperone‐protease networks, the ubiquitin‐proteasome system, and cytosolic surveillance pathways—that together form a dynamic, cell‐wide mitostasis network governing the ...
Lakshita Sharma +5 more
wiley +1 more source
Highly syntenic and yet divergent: a tale of two Theilerias [PDF]
The published genomic sequences of the two major host-transforming Theileria species of cattle represent a rich resource of information that has allowed novel bioinformatic and experimental studies into these important apicomplexan parasites. Since their
Skilton, R. +11 more
core +1 more source
Novel Features of a PIWI-Like Protein Homolog in the Parasitic Protozoan Leishmania
In contrast to nearly all eukaryotes, the Old World Leishmania species L. infantum and L. major lack the bona fide RNAi machinery genes. Interestingly, both Leishmania genomes code for an atypical Argonaute-like protein that possesses a PIWI domain but lacks the PAZ domain found in Argonautes from RNAi proficient organisms.
Prasad K Padmanabhan +5 more
openaire +4 more sources
When can AlphaFold predict the oligomeric states of proteins?
Abstract Homooligomerisation is a prevalent and important process that many proteins undergo to form the quaternary structures required for biological function. However, determining oligomeric states and structures experimentally remains technically challenging and time‐consuming for many proteins.
Yiechang Lin, Ciara Wallis, Ben Corry
wiley +1 more source
Introduction & Objective: Leishmania is a protozoan of the trypanosomatidae family. This protozoan has two stages in its life cycle, promastigote form in sand flies and amastigote form in macrophage of mammalian hosts.
Simindokht Soleimanifard +2 more
doaj
ABSTRACT Giardia lamblia, a protozoan parasite that causes diarrhea in humans, contains two centrins implicated in cellular morphology and cell division. To identify proteins interacting with each G. lamblia centrin (GlCent), we performed a yeast two‐hybrid assay.
Mee Young Shin +2 more
wiley +1 more source
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source

