Results 251 to 260 of about 5,697,775 (262)

Unconventional actins and actin-binding proteins in human protozoan parasites

International Journal for Parasitology, 2015
Actin and its regulatory proteins play a key role in several essential cellular processes such as cell movement, intracellular trafficking and cytokinesis in most eukaryotes. While these proteins are highly conserved in higher eukaryotes, a number of unicellular eukaryotic organisms contain divergent forms of these proteins which have highly unusual ...
C M, Gupta, S, Thiyagarajan, A A, Sahasrabuddhe   +2 more
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Protein synthesis by kinetosomes isolated from the protozoan Tetrahymena

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects, 1962
Abstract An increase in biuret-positive material occurs when kinetosomes isolated from the ciliated protozoan Tetrahymena pyriformis are incubated in a mixture containing amino acids, inorganic phosphorus, uridylic acid, cytidylic acid, guanylic acid, thymine, inosine, MgSO 4 , KF, hexose-diphosphate, ATP, pteroylglutamic acid, riboflavin, vitamin ...
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TLR11 Activation of Dendritic Cells by a Protozoan Profilin-Like Protein

Science, 2005
Mammalian Toll-like receptors (TLRs) play an important role in the innate recognition of pathogens by dendritic cells (DCs). Although TLRs are clearly involved in the detection of bacteria and viruses, relatively little is known about their function in the innate response to eukaryotic microorganisms.
Felix, Yarovinsky, Dekai, Zhang, John F, Andersen, Gerard L, Bannenberg, Charles N, Serhan, Matthew S, Hayden, Sara, Hieny, Fayyaz S, Sutterwala, Richard A, Flavell, Sankar, Ghosh, Alan, Sher   +10 more
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Heat Shock Proteins in Protozoan Parasites – Leishmania spp.

2009
In this review, we shall look into the heat shock proteins of kinetoplastid protozoa of the genus Leishmania. The leishmaniae possess a full complement of molecular chaperones, with peculiar additions. Heat shock proteins play crucial roles in both parts of the biphasic life cycle, having an impact, both on the temperature-induced differentiation from ...
Gabi Ommen, Joachim Clos
openaire   +1 more source

Isotopic labeling of recombinant proteins expressed in the protozoan host Leishmania tarentolae

Protein Expression and Purification, 2006
Isotope labeling of recombinant proteins is a prerequisite for application of nuclear magnetic resonance spectroscopy (NMR) for the characterization of the three-dimensional structures and dynamics of proteins. Overexpression of isotopically labeled proteins in bacterial or yeast host organisms has several drawbacks. In this work, we tested whether the
Niculae, A., Bayer, P., Cirstea, I., Bergbrede, T., Pietrucha, R., Gruen, M., Breitling, R., Alexandrov, K.   +7 more
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In silico identification of the protein disulfide isomerase family from a protozoan parasite

Computational Biology and Chemistry, 2008
Protein disulfide isomerase (PDI) enzymes are eukaryotic oxidoreductases that catalyze the correct formation of disulfide bonds during protein folding. Structurally they are characterized by the presence of functional thioredoxin-like (Trx) domains.
Marco A, Ramos, Rosa E, Mares, Paloma D, Magaña, Joaquín E, Ortega, Jose M, Cornejo-Bravo   +4 more
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Chemical tools for probing protein N-myristoylation in protozoan parasites

2013
Protein N -myristoylation is the attachment of a 14-carbon fatty acid, myristate, onto the N-terminal residue of specific proteins. This co - and post-translational modification is catalysed by myristoyl CoA:protein N -myristoyltransferase (NMT), an essential enzyme in eukaryotes.
openaire   +1 more source

Recombinant Protein Production in the Eukaryotic Protozoan Parasite Leishmania tarentolae: A Review

2011
Leishmania tarentolae is a trypanosomatid protozoan parasite of the gecko, and has been established as a new eukaryotic expression system for the production of recombinant proteins. It seems that a protozoan parasite is a curious choice as the expression host; however, Trypanosomatidae are rich in glycoproteins with a pattern of glycosylation closely ...
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Characterization of factors favoring the expression of soluble protozoan tubulin proteins in Escherichia coli.

Protein Expression and Purification, 2003
L. Macdonald, A. Armson, R. Thompson, Jim A Reynoldson   +3 more
semanticscholar   +1 more source

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins.

Biochemical and Biophysical Research Communications - BBRC, 2000
Roy A. Frye
semanticscholar   +1 more source