Results 41 to 50 of about 48,025 (297)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Displacement shock and recovery in Cyprus [PDF]
Forced Migration Review, 2009 Long-term study of displaced Cypriots suggests that mosthave transcended the shock of displacement.
Peter Loizos
doaj
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Protracted Displacement in the Horn of Africa
TRAFIG Report, 2020 This case study provides an overview on protracted displacement in the Horn of Africa and aims to uncover evidence on transnational and translocal connectivity and mobility of displaced populations in the region. This internal background document contributed to the formulation of TRAFIG Working Paper No 2.
openaire +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Can conflict-generated diasporas be moderate actors during episodes of contested sovereignty? Lebanese and Albanian diasporas compared [PDF]
, 2011 Conflict-generated diasporas are considered likely to maintain radical behaviours. This article seeks to explain why and how they nevertheless adopt moderate claims, especially when advocating highly sensitive issues such as state sovereignty.
Koinova, Maria
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Transnational Figurations of Displacement - Exploring new solutions to protracted displacement
, 2019 According to the UNHCR s latest estimates 15.9 million people are living in protracted refugee situations at the end of the year 2018. This corresponds to more than three-quarter of all refugees. Resolving protracted refugee situations is a fundamental global challenge, yet progress remains stalled.
Noack, Marion +2 more
openaire +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Refugees: asset or burden? [PDF]
Forced Migration Review, 2009 Studying the impact that a refugee population has on itshost country’s economy is important when assessing anddeveloping government refugee strategies, particularly inprotracted refugee situations.
Patricia A Ongpin
doaj