Results 61 to 70 of about 48,025 (297)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Reframing solutions for Afghan refugees
Forced Migration Review, 2014 Regional programming and advocacy in relation to Afghan refugees should be framed around supporting and responding to, rather than ‘solving’, protracted displacement.
Dan Tyler
doaj
Darfur: a way of life lost [PDF]
Forced Migration Review, 2009 The impact of displacement on Darfuris is especially severebecause of the genocidal nature of the violence. It not onlyaffects those millions who are currently displaced but willcontinue to shape the lives of Darfuris for generations to come.
Natalie Ondiak, Omer Ismail
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Forced Migration Review, 2009 The way that mobility is dealt with in respect of protractedrefugee situations shows a gap between social practices andinternational policies.
Giulia Scalettaris
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Europe’s IDPs still marginalised [PDF]
Forced Migration Review, 2009 To bring an end to displacement for some 2.5 million IDPsin Europe, governments’ focus on return must be broadenedto include support and assistance for local integration andsettlement elsewhere in the country.
Nadine Walicki
doaj
Strengthening policy response to protracted displacement - TRAFIG Policy Handbook
, 2022 TRAFIG Policy ...
Wagner, Martin +2 more
openaire +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Cheese tart press machine [PDF]
, 2017 Tart is a type of baked open-pastry which consists of a shortcrust pastry and a filling over it (Figure 9.1). Shortcrust pastry often used as the base for the tart.
Abdul Ghani, Luqman Ul-Hakimi +4 more
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