Results 111 to 120 of about 730,024 (299)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Developing a Partnership Model to Address Gaps in Rural Healthcare Provider Training Using Simulation-Based Health Professions Education. [PDF]

Cureus, 2023
Siraj S, Brunton G, Arutiunian A, Brock G, Dubrowski A.   +4 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Patient and Family-Centered I-PASS SCORE Program: Resident and Advanced Care Provider Training Materials. [PDF]

MedEdPORTAL, 2022
Lewis KD, Destino L, Everhart J, Subramony A, Dreyer B, Allair B, Anderson M, Baird J, Bismilla Z, Good B, Hepps J, Khan A, Kuzma N, Landrigan CP, Litterer K, Sectish TC, Spector ND, Yin HS, Yu CE, Calaman S, O'Toole JK.   +20 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

PedROC 2.0: provider confidence in Wilms tumor management in sub-Saharan Africa: making the case for pediatric radiotherapy inclusion during basic medical training

BMC Medical Education
Background To investigate the relationship between exposure to pediatric radiotherapy during basic medical training and healthcare provider confidence in managing Wilms tumor within sub-Saharan Africa.
Adedayo O. Joseph, Abdul Shour, Azeezat O. Ajose, Paul Phan, Olufunmilayo Fagbemide, Chiedozie Obianyor, Korede Akindele, Adeseye M. Akinsete, Wilfred Ngwa   +8 more
doaj   +1 more source

Telehealth Utilization in Response to the COVID-19 Pandemic: Current State of Medical Provider Training. [PDF]

Telemed J E Health, 2022
DuBose-Morris R, Coleman C, Ziniel SI, Schinasi DA, McSwain SD.   +4 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Is Provider Training Level Associated with First Pass Success of Endotracheal Intubation in the Pediatric Intensive Care Unit? [PDF]

J Pediatr Intensive Care, 2023
Pande CK, Stayer K, Rappold T, Alvin M, Koszela K, Kudchadkar SR.   +5 more
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source