Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Final Vows, Surnames K-L (1 of 2)
Contains the final vows signed by individuals upon becoming members of the Maryland Province.**Former finding aid locations: 119_78_8; 301K-301L*
core
Spatiotemporal patterns and carbon balance zoning optimization of county-level carbon budget in Fujian Province. [PDF]
Zhang S +6 more
europepmc +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Final Vows, Surnames H-J (1 of 2)
Contains the final vows signed by individuals upon becoming members of the Maryland Province.**Former finding aid locations: 119_78_7; 301H-301J*
core
Retraction: Time series expression pattern of key genes reveals the molecular process of esophageal cancer. [PDF]
Wang J, Xie X, Sun Y.
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Final Vows, Surnames Q-T (1 of 2)
Contains the final vows signed by individuals upon becoming members of the Maryland Province.**Former finding aid locations: 119_79_1; 301Q-301T*
core
Correction: The role of microorganisms in the conversion of color class aroma precursors to aroma during air-curing of cigar tobacco leaves. [PDF]
Zhao S +8 more
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source

