Results 111 to 120 of about 927,775 (315)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Andrean examples of mega-geomorphology themes [PDF]
Geomorphic (or physiographic) provinces have been a well known and useful method of regional landform classification for a century. Every earth scientist will recognize a phrase such as Appalachian Plateau or Southern Rocky Mountains as defining a ...
Bloom, A. L.
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
National Finance Commission Awards in Pakistan : A Historical Perspective [PDF]
This study explores the evolution of fiscal resource distribution in Pakistan. Pakistan is a federation comprising four provinces, federallyadministered areas, and the Islamabad Capital Territory.
Iftikhar Ahmed +2 more
core +4 more sources
Factors Influencing the Human Development Index in Iranian Provinces
برنامهریزی و بودجهHuman development is recognized as a modern strand within development economics that has attracted substantial scholarly attention since the 1990s. Within this perspective, enabling individuals to enjoy a long and healthy life, access quality education ...
Ahmad Bakhshi +2 more
doaj
Centripetal Forces in China's Economic Takeoff [PDF]
This paper uses provincial time series data from the People's Republic of China to empirically investigate two propositions relating to economic development: (i) that economic takeoff--or an acceleration in economic growth--is associated with inflows of ...
Aasim M. Husain, Anuradha Dayal-Gulati
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
The current situation of health equity in underserved areas of Afghanistan
Frontiers in Public HealthBackgroundIn Afghanistan, providing universal health coverage (UHC) in accordance with the principles of the UHC declaration is challenging on two fronts: the geographic topography of the country and the prevailing gender dynamics within the local ...
Marwa Rashad Salem +8 more
doaj +1 more source
Industrial Coal Demand in China: A Provincial Analysis [PDF]
The general concern on the environmental implications of the rising demand for coal registered in China during the last few years has induced considerable research effort to produce accurate forecasts of China’s energy requirements.
Cristina Cattaneo +2 more
core
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source