Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Annuaire de l'Institut des provinces et des congrès scientifiques
Variante(s) de titre : Annuaire de l'Institut des provinces, des sociétés savantes et des congrès scientifiquesVariante(s) de titre : Annuaire des sociétés savantes de France et des congrès scientifiquesEtat de collection : 1846-1870 (2e sér., 12e vol ...
Institut des provinces (France). Auteur du texte
core
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Viewpoint from facilities to communities: Breastfeeding promotion in Baby-Friendly Provinces in Türkiye. [PDF]
Aydoğmuş YH +3 more
europepmc +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modeling the effects of meteorological factors and media-driven public awareness on seasonal influenza outbreaks. [PDF]
Liu C +6 more
europepmc +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Integrating migration into cancer geography: spatial clustering of five digestive cancer burden in China. [PDF]
Li G +12 more
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Geriatrician and General Internist Clinical Payments in Canada 2022-2023: Fee for Service and Alternative Payment Plan. [PDF]
Martel AB +4 more
europepmc +1 more source

