Results 211 to 220 of about 363,972 (316)

Moving Forward Together: A Protocol to Co-Adapt and Scale a Videoconference-Delivered Physical Activity Intervention for Children and Adolescents Diagnosed With Cancer or Blood Disorders in British Columbia, Ontario, and the Maritime Provinces. [PDF]

JMIR Res Protoc
Wurz A, Ha L, Sales V, Dani D, Strahlendorf C, Marr K, Lotocka-Reysner H, Lunaczek-Motyka E, Carrelli A, Empringham B, Ramphal R, Mabbott D, Ash C, Flanders A, Stuart M, Consmueller C, Keats MR, McLaughlin E, Culos-Reed SN, Guilcher GM, Fisher S, Chamorro-Viña C, IMPACT Co-Adaptation Advisory Board Members & Research Program Partners and Collaborators.   +22 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Epidemiological Trends and Strain Distribution of Bovine Brucellosis in Vaccinated Industrial Dairy Cattle (2021-2024). [PDF]

Vet Med Int
Alamian S, Amiry K, Bahreinipour A, Dadar M.   +3 more
europepmc   +1 more source

Central Provinces District Gazetteers: Yeotmal District. Vol. A

, 1908
Brown, C, Russell, RV, Central Provinces District Gazetteers   +2 more
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Syndemic analysis of stroke in Indonesia. [PDF]

Lancet Reg Health West Pac
Zainuddin AA, Kadir RRA, Qalby N, Kuswanto H, Abdullah AA, Furusawa T, Rasyid H, Yusuf I.   +7 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Geographical Inequalities in Mortality by Age and Gender in Italy, 2002-2019: Insights from a Spatial Extension of the Lee-Carter Model. [PDF]

Spat Demogr
Fiori F, Riebler A, Martino S.
europepmc   +1 more source

Report of the Co-operative Committee of the United Provinces of Agra and Oudh, 1926

, 1926
United Provinces Co-operative Committee
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source