Results 81 to 90 of about 363,972 (316)

Migration and commuting interactions fields: a new geography with community detection algorithm?

open access: yesBelgeo, 2017
The objective is to refresh the geography of Belgium using interactions between places by means of a community detection algorithm (Louvain Method) inspired by Complex theory and Data Sciences. Places that are tightly related are optimally clustered into
Isabelle Thomas   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Report on the administration of the N.-W. Provinces and Oudh, for the year ending 31st March ...

open access: yes
Description based on: 1886.Mode of access: Internet.Formed by the union of: North-Western Provinces, India. Report on the administration of the N.W. Provinces; and: Oudh (India).
Oudh (India)   +1 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

LA PRIMERA DIVISIÓN POLÍTICO-ADMINISTRATIVA DE CHILE, 1811-1826

open access: yesHistoria (Santiago), 2008
En este trabajo sostenemos que, debido a la Independencia y a la consecuente formación del Estado chileno, el país se vio en la necesidad de recurrir a una nueva división interna del territorio nacional con el objeto de establecer un ordenamiento ...
María Carolina Sanhueza
doaj  

Development and Sources of Labor Productivity in Chinese Provinces [PDF]

open access: yes
As China exhibited unprecedented rapid economic growth ever since its reform and openness, the development and sources of labor productivity has gradually come to the forefront.
Su, Biwei, Heshmati, Almas
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Economic growth across Chinese provinces: in search of innovation-driven gains [PDF]

open access: yes
In this paper we analyse the impact of R&D on total factor productivity across Chinese provinces. We introduce innovations explicitly into a production function and evaluate their contribution to economic growth in 1993 - 2006.
Yu, Hao, Funke, Michael
core  

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