Results 61 to 70 of about 29,235 (219)

Napabucasin transforms liver microenvironment and boosts immunotherapy efficacy by converting potential metastases into “hot” tumors

Interdisciplinary Medicine, EarlyView.
Napabucasin reduces liver metastases by reprogramming the hepatic microenvironment. It induces hepatocyte secretion of CCL21 via c‐Fos activation, recruiting lymphocytes and converting “cold” metastases into immunologically “hot” tumors. This effect is liver‐specific and independent of cancer cells.
Qiongqiong Wang, Jiaqi Zhou, Hang Qiao, Yifan Jia, Ling Ye, Zeli Li, Jiahe Ouyang, Haoxian Zhou, Kangxin Zeng, Xuemeng Wang, Yixian Wang, Yang Zhang, Yupeng Zhang, Yizhou Cai, Yutao Hu, Minzhe Zhang, Wenwei Xu, Zhenzhen Wu, Xiaofang Qiu, Li Lin   +19 more
wiley   +1 more source

Sleep deprivation aggravates hepatocytes steatosis and insulin resistance by regulating exosomal microRNAs

Interdisciplinary Medicine, EarlyView.
Sleep deprivation accelerates the progression of MASLD and IR by up‐regulating the expression of miR‐3572‐5p and down‐regulating the expression of miR‐183‐5p in circulating exosomes, thereby inhibiting fatty acid β‐oxidation and disrupting insulin signaling pathways. Abstract Sleep deprivation (SD) threatens human health and increases the prevalence of 
Xinxin Xu, Lulu Li, Ying Cao, Ying Wang, Chao Yang, Alexander Nikolaevich Orekhov, Yuanfeng Lu, Houbin Chu, Chuanrong Zhao, Guixue Wang, Guohua Song   +10 more
wiley   +1 more source

Assessment of Disease Severity and Quality of Life in Patients with Atopic Dermatitis from South Korea. [PDF]

Ann Dermatol, 2022
Son SW, Lee JH, Ahn J, Chang SE, Choi EH, Han TY, Jang YH, Kim HO, Kim MB, Kim YC, Ko HC, Ko JY, Lee SE, Lee YW, Lew BL, Na CH, Park CO, Park CW, Park KY, Park K, Park YL, Roh JY, Seo YJ, Shin MK, Lee S, Cho SH.   +25 more
europepmc   +1 more source

China Employment Law Update - April 2011 [PDF]

, 2011
[Excerpt] From May 1, 2011, it will be a criminal offence for a company to intentionally fail to pay wages as a result of an amendment implemented by the National People’s Congress to PRC Criminal Law (“the Amendment”).
Baker & McKenzie
core   +1 more source

Between Dependence and Alienation: Understanding the Digital Minimalist Behavior of Chinese Millennials—An Analysis Based on SEM and fsQCA

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Following rapid iterations in media technologies, Chinese millennials (born between 1980 and 1995) find themselves in a paradoxical state where digital saturation exists alongside fatigue, making them central practitioners of digital minimalist behavior.
Chao Zhang, Yinze Hao, Jingwen Li
wiley   +1 more source

The Non‐Professional Virtues of the Hospice Volunteer

Journal of Applied Philosophy, EarlyView.
ABSTRACT Volunteers have long played a significant role in hospice care. Much of the care volunteers provide consists of weekly hour‐long in‐home visits. Home‐visiting hospice volunteers are not professionals, nor are they strangers or intimates. Hospice volunteers will not typically face moral dilemmas, nor be called upon to make dramatic decisions ...
Michael B. Gill
wiley   +1 more source

A Pedagogy of Belonging: Strategies and Practices for Building Beloved Community in Counselor Education

The Journal of Humanistic Counseling, EarlyView.
ABSTRACT With an increased need for counselors across the country, there is a corresponding need to recruit and retain quality graduate students in counseling programs. Using bell hooks’ framework of beloved community, this conceptual article explores how to develop a sense of belonging in counselor education among students of diverse identities inside
Ellise Nolan, Madeline Clark
wiley   +1 more source

Assessing the performance of a method for case-mix adjustment in the Korean Diagnosis-Related Groups (KDRG) system and its policy implications. [PDF]

Health Res Policy Syst, 2021
Kim S, Choi B, Lee K, Lee S, Kim S.
europepmc   +1 more source

Effect of in situ amylase and fermented maize starch on texture and after‐cooking storability of lafun dough

JSFA reports, EarlyView.
Abstract Background Lafun is made by fermenting and drying cassava chunks, which are then milled into flour and cooked into dough. Its quality characteristics are variety‐dependent, while it may become too soft or even liquefy during storage, leading to rejection by end‐users.
Laurent Adinsi, Muqsita Daouda, Alexandre Bouniol, Sègla Wilfrid Padonou, Imayath Djibril Moussa, Francis Hotegni, Noël Akissoé   +6 more
wiley   +1 more source

Flexicurity in Belgium: A Proposal Based on Economic Principles [PDF]

The current unemployment insurance and employment protection legislation were set up in an economic environment in which relationships between workers and firms were typically long-lasting and stable.
Cockx, Bart, Van der Linden, Bruno
core