This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun +19 more
wiley +1 more source
Full-Arch Oral Rehabilitation in All-on-4 "M" Configuration Using Surgical Guides with Internal Cooling: A Clinical Case Report. [PDF]
Tuce RA +4 more
europepmc +1 more source
Young people not in education, employment or training (NEET), year to 30 September 2012 [PDF]
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Localized NF‐κB Inhibition Reduces Lipid Nanoparticle‐Associated Inflammation
Lipid nanoparticles (LNPs) activate NF‐κB and provoke inflammation that limits therapeutic delivery. By encapsulating selective NF‐κB inhibitors within LNPs, localized suppression of inflammatory signaling is achieved without compromising mRNA expression.
Carolann L. Espy +16 more
wiley +1 more source
Cumulative Summation (CUSUM)-as a tool for objective analysis of learning curve for surgeons in acquiring competency in phacoemulsification. [PDF]
Ng EMC +4 more
europepmc +1 more source
Comparing Multi-Label Classification Methods for Provisional Biopharmaceutics Class Prediction. [PDF]
Freitas, Alex A. +2 more
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Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason +12 more
wiley +1 more source
Preservation of Dental Structure in Prosthetic Restorations: Vertical and Horizontal Preparation Techniques. Systematic Review. [PDF]
Florescu ML +6 more
europepmc +1 more source
Further Education Funding Council : circular 00/03 : funding : funding guidance 2000-01 [PDF]
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Despite widespread exposure, the mechanisms of manganese neurotoxicity remain poorly understood. Using correlative cryogenic fluorescence and synchrotron X‐ray fluorescence imaging techniques, we show that the Golgi apparatus is the primary accumulation site for manganese in both neurons and astrocytes, and that manganese targets the neuronal ...
Ines Kelkoul +12 more
wiley +1 more source

