Results 191 to 200 of about 256,307 (296)

Challenging Case: Health Care Professionals as Cultural Brokers for a Boy From Central America With Attention-Deficit Hyperactivity Disorder and Trauma and Stressor-related Disorder. [PDF]

J Dev Behav Pediatr
Cerda N, Shahidullah JD, Kates C, Marquez A, Diekroger EA, Fogler J.   +5 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Consensus Report of Group 1 of the 1st Global Consensus for Clinical Guidelines for the Rehabilitation of the Edentulous Maxilla: Number of Implants, Timing of Implant Placement and Loading. [PDF]

Clin Oral Implants Res
Donos N, Ng E, Pannuti CM, Romito GA, Francisco HCO, Abou-Ayash S, Avila-Ortiz G, Carames JMM, Casentini P, Chackartchi T, Chappuis V, Chen S, Fugazzotto P, Giannobile WV, Hagiwara Y, Hamilton A, Ivanovski S, Kahn S, Kan J, Lambert F, Levine RA, Navarro JM, Ornekol T, Payer M, Schoenbaum T, Singh MK, Thacker S, Alcoforado G.   +27 more
europepmc   +1 more source

In Vivo CRISPR Screening Identifies the Glutamate Receptor GRIA2 as Promoting Peritoneal Metastasis of Gastric Cancer via Calcium‐Dependent β‐Catenin Activation

Advanced Science, EarlyView.
We identified GRIA2 as a critical driver of gastric cancer peritoneal metastasis through in vivo CRISPR screening. Mechanistically, GRIA2‐mediated calcium influx inhibits GSK3β and activates Wnt/β‐catenin signaling, driven by glutamate from cancer‐associated fibroblasts.
Jie Sun, Xu Yang, Wenchao Jiang, Chengbo Ji, Yingying Wu, Haoyu Sun, Xinyou Liu, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Junjie Zhao, Yuanyuan Ruan, Haojie Li, Xuefei Wang   +13 more
wiley   +1 more source

In vitro evaluation of color characterization, mechanical properties, and antimicrobial activity of 3D-printed provisional dental resin incorporated with Ficus carica (Fig) seed extract. [PDF]

J Oral Biol Craniofac Res
Jei JB, Muthukumar B.
europepmc   +1 more source

Young people not in education, employment or training (NEET) : year to 30 June 2011 [PDF]

, 2012

core  

Self‐Nitriding Nanostructured Transition Metal Nitrides in Architected‐Carbon Matrices: Unveiling Mechanisms and Advancing Performance in Lithium‐Sulfur Pouch Cells

Advanced Science, EarlyView.
Imidazolium PIL nanoparticles, as an N‐rich template and morphology director, enable a colloidal self‐nitriding route to TMNs (VN, Mo2N) within controlled solid/hollow carbon architectures. As sulfur hosts/additives, TMNs accelerate Li–S redox kinetics and support high‐loading cathodes.
Yael Rodriguez Ayllon, Liqiang Lu, Dongjiu Xie, Xuefeng Pan, Teodor Jianu, Fangmu Qu, Sijia Cao, Yu Zhang, Roberto Félix, Marcus Bär, Nadezda V. Tarakina, Johannes Schmidt, Qingping Wu, Jiayin Yuan, Yan Lu   +14 more
wiley   +1 more source

Two-Year Outcomes of Regenerative Therapy in an Immature Maxillary Molar With Periapical Abscess: A Case Report. [PDF]

Case Rep Dent
Siqueira LFR, de Souza-Guedes TC, Araujo LF, Pereira PRS, Veríssimo C, de Siqueira PC, Miguel JG, Guedes OA, Chaves GS.   +8 more
europepmc   +1 more source

National curriculum assessments at key stage 2 in England, 2011/2012 (revised) [PDF]

, 2012
Attew, Karen
core  

Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China

Advanced Science, EarlyView.
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang, Yadong Yang, Yongsheng Wang, Guirui Yu   +3 more
wiley   +1 more source