Results 91 to 100 of about 1,044,602 (311)
European Company Survey on Reconciliation of Work and Family Life [PDF]
, 2010 [Excerpt] Demographic change requires an increase in labour force participation. This applies partic- ularly to those groups which have had relatively low participation rates in the past and those with family obligations such as child rearing or care for
Federal Ministry for Family Affairs, Senior Citizens, Women and Youth
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
PARTICULAR ASPECTS RELATING TO THE RIGHT TO PRIVATE AND FAMILY LIFE OF PERSONS DEPRIVED OF THEIR LIBERTY IN THE LIGHT OF ART. 8 ECHR [PDF]
Challenges of the Knowledge SocietyBasically, the scope of art. 8 ECHR is to protect individuals against arbitrary interference of public authorities with their private and family life. The need to comply with this desideratum may require certain positive obligations on a State to ensure ...
Nicolae-Cătălin MAGDALENA +1 more
doaj
Recent Changes to Canada's Financial Sector Legislation [PDF]
Significant legislative developments have occurred in Canada's financial services sector over the past decade. This article chronicles those developments and gives an overview of the key provisions contained in Bill C-8, the legislation to reform the ...
Fred Daniel
core
Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja +8 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source