Results 111 to 120 of about 9,468 (203)
Mechanisms of PROX1 mediated regulation of the lymphatic endothelial cell cycle
The homeobox transcription factor PROX1 is the mammalian ortholog of the Drosophila gene Prospero. Expression of PROX1 in a subset of venous endothelial cells changes their fate to lymphatic endothelial cells (LEC).
Baxter, Shannon A.
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Guomiao Su,1,* Juan Wang,2,* Shiyue Liu,1,* Xiaonan Fu,1 Yanxi Li,1 Guoqing Pan1 1Department of Pathology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yun Nan, People’s Republic of China; 2Clinical Laboratory, Yunnan
Su G, Wang J, Liu S, Fu X, Li Y, Pan G
doaj
Reprogramming via Prox1 in double transgenics is restricted to veins.
Immunohistochemistry on E13.5 controls and double transgenics stained with (A and C) Podoplanin or (B and D) LYVE-1. While the jugular veins of DT embryos stained positive for both markers (C and D, arrows), the dorsal aortas did not (arrowheads).
Annie Bourdeau (103746) +3 more
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Transcription factor PROX1 modifies Wnt signaling in colon cancer
PR0X1 est un facteur de transcription très conservé au cours de l'évolution. PROX1 joue un rôle essentiel dans de nombreuses étapes de l'embryogenèse, telles que le développement du système lymphatique ou la migration des hépatocytes. Récemment, il a été
Cheng, J.
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Objective The current study aimed to investigate the prognostic relevance of PROX1, and MTA1 in salivary gland carcinomas. Methods In a retrospective study on 45 cases diagnosed with salivary gland carcinoma, PROX1 and MTA1 immunoexpressions were ...
Samar Soliman +2 more
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The Role of Protein-Protein Interactions in Controlling Prox1 Function
Prox1 is a homeodomain transcription factor that is important for controlling lens, liver, pancreatic, and lymphatic system development. Prox1 has also been implicated in the regulation of tumor suppressor genes and the onset of cancer. Despite this wide
Isaacs, Lauren H.
core
The role of Prox1 in metabolism-mediated regulation of neurogenesis
Emerging evidence suggests that a metabolic switch from glycolysis to oxidative phosphorylation in neural stem/progenitor cells (NSCs) is a key regulatory event for the induction of neurogenesis. The self-renewing NSCs rely on glycolysis, while down-regulation of glycolysis and enhancement of oxidative phosphorylation (OXPHOS) is required for their ...
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