Results 171 to 180 of about 9,468 (203)
Distinct roles of the Lyve1 lineage in heart development
Klaourakis K +7 more
europepmc +1 more source
Prox1 expression in rod precursors and Müller cells
Experimental Eye Research, 2010 [EN]The transcription factor Prox1 acts in rodent retinogenesis, at least in promoting cell cycle withdrawal and horizontal cell production. In the mature retina, this protein is detected at the inner nuclear layer of all vertebrate groups.
Juan Lara +2 more
exaly +5 more sources
Transcription factor PROX1: its role in development and cancer
Cancer and Metastasis Reviews, 2012 The homeobox gene PROX1 is critical for organ development during embryogenesis. The Drosophila homologue, known as prospero has been shown to act as a tumor suppressor by controlling asymmetric cell division of neuroblasts. Likewise, alterations in PROX1
Mónica Nistér +2 more
exaly +5 more sources
Prox1 is differentially localized during lens development
Mechanisms of Development, 2002 Prox1, the vertebrate cognate of Drosophila Prospero, is a homeodomain protein essential for the development of the lens, liver and lymphatic system. While it is well established that the subcellular distribution of Prospero changes during development, this had not been demonstrated for Prox1. Here, high-resolution confocal microscopy demonstrated that
Melinda K Duncan, Stanislav I Tomarev
exaly +3 more sources
Ras Pathways on Prox1 and Lymphangiogenesis: Insights for Therapeutics [PDF]
Frontiers in Cardiovascular Medicine, 2020 Over the past couple of decades, lymphatics research has accelerated and gained a much-needed recognition in pathophysiology. As the lymphatic system plays heavy roles in interstitial fluid drainage, immune surveillance and lipid absorption, the ablation or excessive growth of this vasculature could be associated with many complications, from ...
Young-Kwon Hong
exaly +4 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
A Prox1 enhancer represses haematopoiesis in the lymphatic vasculature
Nature, 2023Transcriptional enhancer elements are responsible for orchestrating the temporal and spatial control over gene expression that is crucial for programming cell identity during development1-3. Here we describe a novel enhancer element that is important for regulating the expression of Prox1 in lymphatic endothelial cells.
Jan Kazenwadel +14 more
openaire +5 more sources
PROX1 is a predictor of survival for gliomas WHO grade II [PDF]
British Journal of Cancer, 2011 The clinical course of World Health Organisation grade II gliomas remains variable and their time point of transformation into a more malignant phenotype is unpredictable. Identification of biological markers that can predict prognosis in individual patients is of great clinical value.
Mikael S Lindstrom, Anja Smits
exaly +3 more sources
Production of Monoclonal Antibodies Against Prox1
Hybridoma, 2006Prox1 is a divergent homeodomain protein important for the development of the lens, retina, liver, pancreas, and lymphatic vasculature. Prox1 expression is highly upregulated in transformed hepatocytes and has been used as a marker to distinguish lymphatic from blood vasculature.
Xiaoren, Chen +3 more
openaire +2 more sources
Biochemical and Biophysical Research Communications, 2015
This study describes a technical breakthrough in endolymphatic sac research, made possible by the use of the recently generated Prox1-GFP transgenic mouse model. Whole-mount imaging techniques through the decalcified temporal bone and three-dimensional observations of Prox1-GFP mouse tissue revealed the positive labeling of the endolymphatic sac in ...
Takenori, Miyashita +7 more
openaire +2 more sources
This study describes a technical breakthrough in endolymphatic sac research, made possible by the use of the recently generated Prox1-GFP transgenic mouse model. Whole-mount imaging techniques through the decalcified temporal bone and three-dimensional observations of Prox1-GFP mouse tissue revealed the positive labeling of the endolymphatic sac in ...
Takenori, Miyashita +7 more
openaire +2 more sources
Prox1, master regulator of the lymphatic vasculature phenotype
Cell and Tissue Research, 2003In contrast to the extensive molecular and functional characterization of blood vascular endothelium, little is known about the mechanisms that control the formation and lineage-specific differentiation and function of lymphatic vessels. The homeobox gene Prox1, the vertebrate homologue of the Drosophila prospero gene, has been recently identified to ...
Young-Kwon, Hong, Michael, Detmar
openaire +2 more sources