Results 61 to 70 of about 51,124 (249)

Case report: Rapid clinical improvement of anti-HMGCR immune-mediated necrotizing myopathy treated with efgartigimod

Frontiers in Immunology
Immune-mediated necrotizing myopathy (IMNM) with anti-HMGCR antibody positivity is characterized by proximal extremity weakness, increased creatine kinase, and extensive muscle edema. There is an urgent need to find more appropriate treatment options for
Quantao Zeng, Kai Chen, Li Zeng, Lixia Xu, Song Tan, Song Tan   +5 more
doaj   +1 more source

PROXIMAL MUSCLE WEAKNESS RESPONDING TO SELENIUM THERAPY: A CASE REPORT [PDF]

Pediatric Research, 1984
Van Rij reported proximal muscle weakness in a case of selenium (Se) deficiency in New Zealand in 1979. Since then cardiomyopathy, but not proximal muscle weakness, has been reported in the USA. A 33 y.o. white female was on home parenteral nutrition for 4½ years due to a duodenocecostomy secondary to a traumatic jejunoilectomy.
M R Brown, J M Lyons, T W Curtis, B Thunberg, W J Cochran, W J Klish, H J Cohen   +6 more
openaire   +1 more source

Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review

Advanced Functional Materials, EarlyView.
Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera, Chiranjeevi Kanike, Appurva Tiwari, Hongyan Wu, Larry D. Unsworth, Ben Bin Xu, Xuehua Zhang   +6 more
wiley   +1 more source

Proximal Limb Weakness Reverting After CSF Diversion In Intracranial Hypertension

Annals of Indian Academy of Neurology, 2005
We report about two young girls who developed progressive visual failure secondary to increased intracranial pressure and had significant proximal muscle weakness of limbs.
Sinha S, Taly A,B, Pramod M.N, Indira Devi B, Satish S, Kovur JME, Singhai A.K, Arunodaya G.R   +7 more
doaj  

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng, Camila B. Tovani, Simona Bianco, Gianni Comandini, Aya Elghajiji, Mina Aleemardani, Roxana Moscalu, Jeremie Zappia, Bianca Fernandes, Olivia Annett, Chrissy L. Hammond, Jason Wong, Dave J. Adams, Fabrizio Scarpa, Michael R. Whitehouse, Annela M. Seddon, James P. K. Armstrong   +16 more
wiley   +1 more source

Waddling Gait: A complication of valproate therapy and a thought beyond vitamin D deficiency

Sultan Qaboos University Medical Journal, 2020
Proximal muscle weakness is a common presentation in paediatric-orthopaedic clinics and is frequently paired with a vitamin D deficiency diagnosis.
Amit Sharma, Siddhartha Sinha, Amit Narang, Dushyant K. Chouhan, Sumit Gupta   +4 more
doaj   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

Hierarchical Structure and Fabrication of Functionally Graded Biointerfaces in the Mussel Byssus

Advanced Materials Interfaces, EarlyView.
The byssus is a fibrous protein‐based holdfast consisting of mechanically distinct interfaces, which mussels use to anchor their soft living tissue to hard seashore surfaces. Here, multiscale methodologies were used to elucidate the compositional and structural features underlying these functionally graded interfaces and how they are fabricated through
Lucia Youssef, Jenaes Sivasundarampillai, Sydney Mikulin, Franziska Jehle, Matthew J. Harrington   +4 more
wiley   +1 more source

Expanding the phenotypic and imaging spectrum of GFPT1-related congenital myasthenic syndromes: a Brazilian case series

Frontiers in Neurology
IntroductionGFPT1-related congenital myasthenic syndrome (CMS) is a rare, autosomal recessive disorder that impairs neuromuscular transmission due to defective glycosylation of the neuromuscular junction.
Antonio Edvan Camelo-Filho, Gustavo Rodrigues Ferreira Gomes, Pedro Lucas Grangeiro Sá Barreto Lima, Vitória Maria Torres Peixoto, Tamiris Mariano, Ellen Mourão Soares Lopes, Raquel Diógenes Alencar, Paulo Ribeiro Nóbrega, André Luiz Santos Pessoa   +8 more
doaj   +1 more source