Results 251 to 260 of about 93,932 (331)

ASK1 limits kidney glucose reabsorption, growth, and mid-late proximal tubule KIM-1 induction when diabetes and Western diet are combined with SGLT2 inhibition. [PDF]

Am J Physiol Renal Physiol
Crespo-Masip M, Goodluck HA, Kim YC, Oe Y, Roach AM, Kanoo S, Lopez N, Zhang H, Badal SS, Vallon V.   +9 more
europepmc   +1 more source

A guide to heat shock factors as multifunctional transcriptional regulators

The FEBS Journal, EarlyView.
The heat shock factors (HSFs) are evolutionarily conserved transcription factors best known as regulators of molecular chaperone genes in response to heat shock and other protein‐damaging stresses. Vertebrate HSFs, HSF1‐5, HSFX, and HSFY, are implicated in various physiological and pathological processes, including organismal development and cancer ...
Hendrik S. E. Hästbacka, Alejandro J. Da Silva, Lea Sistonen, Eva Henriksson   +3 more
wiley   +1 more source

Proximal tubule hypertrophy and hyperfunction: a novel pathophysiological feature in disease states. [PDF]

Clin Kidney J
Kanbay M, Copur S, Guldan M, Ozbek L, Hatipoglu A, Covic A, Mallamaci F, Zoccali C.   +7 more
europepmc   +1 more source

A guide to characterizing the dynamic mitochondria–endoplasmic reticulum contact sites

The FEBS Journal, EarlyView.
The dynamism, heterogeneity, and functional complexity of mitochondria–endoplasmic reticulum contacts (MERCs) require combined methodological approaches to offset limitations of individual techniques. Here, we review available tools and methodologies for MERC research, outline key technical challenges, and discuss how recent advances deliver ...
Antigoni Diokmetzidou, Luca Scorrano
wiley   +1 more source

Podocyte-specific KLF6 primes proximal tubule CaMK1D signaling to attenuate diabetic kidney disease. [PDF]

Nat Commun
Gujarati NA, Frimpong BO, Zaidi M, Bronstein R, Revelo MP, Haley JD, Kravets I, Guo Y, Mallipattu SK.   +8 more
europepmc   +1 more source

Hormones and nocturia : guidelines for medical treatment? [PDF]

, 2014
Everaert, Karel, Goessaert, An-Sofie, Kapila, Ayush, Vande Walle, Johan   +3 more
core   +1 more source

Tks5 interactome reveals endoplasmic‐reticulum‐associated translation machinery in invadosomes

The FEBS Journal, EarlyView.
Invadosomes—dynamic structures enabling matrix invasion—include rosettes, dots, and linear forms, depending on cell type and context. Using the invadosome marker Tks5 (SH3PXD2A), we identified shared molecular features across cell types. Mass spectrometry revealed components of the translation machinery, notably EIF4B, and ER‐associated proteins within
Léa Normand, Benjamin Bonnard, Margaux Sala, Sylvaine Di Tommaso, Cyril Dourthe, Anne‐Aurélie Raymond, Jean‐William Dupuy, Luc Mercier, Jacky G. Goetz, Violaine Moreau, Elodie Henriet, Frédéric Saltel   +11 more
wiley   +1 more source

Yapping at the autophagy door? The answer is flowing in the kidney proximal tubule. [PDF]

Autophagy
Claude-Taupin A, Terzi F, Codogno P, Dupont N.   +3 more
europepmc   +1 more source

Cell membranes and paracellular resistances in isolated renal proximal tubules from rabbit and Ambystoma.

, 1986
Elsa Bello‐Reuss
openalex   +1 more source

Effectiveness and tolerability of liraglutide as add‐on treatment in patients with obesity and high‐frequency or chronic migraine: A prospective pilot study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To assess whether glucagon‐like‐peptide‐1 receptor (GLP‐1R) agonists could serve as a novel prophylactic treatment for migraine in patients with obesity. Background Increased intracranial pressure (ICP) is speculated to play a role in migraine mechanisms, as chronic migraine and idiopathic intracranial hypertension without ...
Simone Braca, Cinzia Valeria Russo, Antonio Stornaiuolo, Gennaro Cretella, Angelo Miele, Caterina Giannini, Roberto De Simone   +6 more
wiley   +1 more source