Results 331 to 340 of about 611,505 (395)

Generation of a conditional cellular senescence model using proximal tubule cells and fibroblasts from human kidneys. [PDF]

Cell Death Discov
Shao X, Xu H, Kim H, Ljaz S, Beier F, Jankowski V, Lellig M, Vankann L, Werner JN, Chen L, Ziegler S, Kuppe C, Zenke M, Schneider RK, Hayat S, Saritas T, Kramann R.   +16 more
europepmc   +1 more source

Pik3c3 expression profiling in the mouse kidney and its role in proximal tubule cell physiology.

Am J Physiol Cell Physiol
Liu T, Yuan J, Dai C, Chen MX, Fan J, Humphreys BD, Fulton DJR, Kleven DT, Fan X, Dong Z, Chen JK.   +10 more
europepmc   +1 more source

Transcriptomics of SGLT2-positive early proximal tubule segments in mice: response to type 1 diabetes, SGLT1/2 inhibition, or GLP1 receptor agonism.

Am J Physiol Renal Physiol
Kim YC, Das V, Kanoo S, Yao H, Stanford SM, Bottini N, Karihaloo A, Vallon V.   +7 more
europepmc   +1 more source

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Sweet phosphate in the proximal tubule.

Kidney International
P. Houillier
semanticscholar   +3 more sources

Androgens augment proximal tubule transport

American Journal of Physiology-Renal Physiology, 2004
The proximal tubule contains an autonomous renin-angiotensin system that regulates transport independently of circulating angiotensin II. Androgens are known to increase expression of angiotensinogen, but the effect of androgens on proximal tubule transport is unknown.
Albert, Quan, Sumana, Chakravarty, Jian-Kang, Chen, Jian-Chun, Chen, Samer, Loleh, Neel, Saini, Ray C, Harris, Jorge, Capdevila, Raymond, Quigley   +8 more
openaire   +2 more sources

The Renal Proximal Tubule

1979
Methodologic as well as conceptual progress during the past decade has made it possible for renal physiologists to “peek” inside the epithelial “black box” of renal tubular function with a greater degree of confidence than ever before. Among the more important developments have been: (1) evolution of the fluid mosaic model of plasma membrane structure (
M, Silverman, R J, Turner
openaire   +2 more sources

Potassium channels in Necturus proximal tubule

American Journal of Physiology-Renal Physiology, 1987
Potassium channels from the apical and basolateral membranes of Necturus proximal tubule were studied using the patch-clamp technique. The conductance of the basolateral channel was dependent on the pipette K+ concentration (apparent Km, 65.5 mM K+; maximum channel conductance, 49.8 pS). The permeability ratio (PK+/PNa+) was approximately 10:1.
K, Kawahara, M, Hunter, G, Giebisch
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Disorders of the Renal Proximal Tubule

Nephron Physiology, 2010
Following glomerular filtration, the bulk of solutes are reabsorbed in the proximal tubule to prevent excessive losses of vital metabolites. In this nephron segment, reabsorption is largely active via dedicated transporters. Hereditary defects in proximal tubular function are characterized by malabsorption affecting amino acids, glucose, potassium ...
Bokenkamp, A., Ludwig, M.
openaire   +4 more sources

Water Permeability in Rat Proximal Tubules

Acta Physiologica Scandinavica, 1970
AbstractThe diffusional water permeability in rat proximal tubules was studied in microperfusion experiments with triturated water. The perfusion solutions were chosen either to give no net flux or a net water flux in either direction. The diffusional water permeability at zero net water flux was 564. 10‐‐5 cm/sec.
E, Persson, H R, Ulfendahl
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Proximal tubule response in aldosterone escape

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1989
The response of the proximal tubule to chronic aldosterone administration (15 micrograms.kg-1.day-1) was evaluated in eight conscious female mongrel dogs. Temporal profiles between hemodynamic and hormonal changes and the fractional excretions of sodium and lithium were established.
J M, Gonzalez-Campoy, J, Kachelski, J C, Burnett, J C, Romero, J P, Granger, F G, Knox   +5 more
openaire   +2 more sources