Results 91 to 100 of about 64,618 (296)

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Sistem Pengaturan Palang Pintu Perlintasan Kereta Api Terintegrasi Sensor Proximity dan Sensor Vibrasi Berdasarkan Real Time Clock (RTC) [PDF]

open access: yes, 2021
Telah dilakukan penelitian sistem pengaturan palang pintu perlintasan kereta api terintegrasi sensor proximity dan sensor vibrasi berdasarkan real time clock (RTC) yang dapat menghasilkan sistem monitoring untuk palang pintu perlintasan kereta api ...
Ariski, Ariski
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Control of a Snake Robot With Proximity Sensors to Adapt for Two Variable Planes

open access: yesIEEE Access
This paper proposes a control method for a snake robot to move between two planes amidst changing environmental conditions. The proposed approach uses a proximity sensor affixed to the robot to estimate its position and orientation relative to the plane.
Shunta Suyama   +3 more
doaj   +1 more source

Handsight: Hand-Mounted Device untuk Membantu Tunanetra Berbasis Ultrasonic dan Arduino

open access: yesJurnal Teknologi dan Sistem Komputer, 2015
Generally, blind people use a cane to know the distance around them. A cane was normally use when they walk outdoors, but if the cane used in indoors; it is not used because of fear of damaging the goods-glassware.
Eko Setyo Purnomo   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

A Low Power IoT-Connected Smart Canister System Creating Automatic Shopping List

open access: yesJournal of Sensor and Actuator Networks, 2019
One of the most common forgotten things of adults is that they go to the shops and completely forget what they went for. The solution to this problem is to carry a shopping list.
Tareq Khan
doaj   +1 more source

Implementasi sensor proximity pada pembuatan “trap mouse”

open access: yes, 2020
Tujuan pembuatan alat ini adalah untuk merancang dan membuat sebuah automatic mousetrap (perangkap tikus otomatis) menggunakan sensor proximity berbasis arduino uno.Merealisasikan sebuah alat bantu yang dapat digunakan dengan cara yang lebih mudah. Alat
ZIKRI, MUHAMMAD
core  

Capacitive proximity sensor design tool based on finite element analysis

open access: yes, 2010
PurposeThe purpose of this paper is to develop a program based on three‐dimensional finite element analysis to model different patterns of capacitive proximity sensors.
Fahimeh Dehkhoda   +2 more
core   +1 more source

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