Results 31 to 40 of about 617,408 (262)
Impact of non-thermal variables on hydroxylated GDGT distributions around Iceland
Frontiers in Earth ScienceArchaeal isoprenoid glycerol dibiphytanyl glycerol tetraethers (GDGTs) preserved in sediments are popular tools for the reconstruction of past temperature in the global ocean. Whereas the most common GDGTs have been well studied through environmental and
David J. Harning +2 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Physical Therapy Korea, 2021 Background: Researchers have previously commenced examining the degree of concordance between parent proxy and child self-reports on health-related quality of life (HRQOL) of many disease and impairment populations. Objects: To explore the differences
Bongsam Choi
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Applied Sciences, 2020 HTTP/2 video streaming has gotten a lot of attention in the development of multimedia technologies over the last few years. In HTTP/2, the server push mechanism allows the server to deliver more video segments to the client within a single request in ...
Chanh Minh Tran +3 more
doaj +1 more source
An Improved Web Caching System With Locally Normalized User Intervals
IEEE Access, 2021 Caching is one of the most promising areas in the field of future internet architecture like Information-centric Networking, Software Defined Networking, and IoT.
Krishnakumar Vaithinathan +5 more
doaj +1 more source
The agreement between proxy and self-completed EQ-5D for care home residents was better for index scores than individual domains [PDF]
, 2014 Objective: Proxy measures are an alternative source of data for care home residents who are unable to complete the health utility measure, but the agreement levels between residents and care home staff for the EQ-5D have not been investigated previously.
Diaz-Ordaz, Karla +6 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Failing the vulnerable: Three new consent norms that will undermine health research with children
Southern African Journal of HIV Medicine, 2014 The South African National Health Act (No. 61 of 2003) provides a legal framework for the regulation of the health system across the country. Within the Act, section 71 introduces a number of legal norms relating to research or experimentation with human
Ann Strode +4 more
doaj +1 more source
Frontiers in Marine Science, 2020 Nutrient loading from land masses pose a serious threat to coastal ecosystem functioning. In this study the hypothesis involving applicability of a benthic foraminiferal genus, Ammonia as a reliable proxy for tracking sediment organic carbon load was ...
Punyasloke Bhadury +2 more
doaj +1 more source