Results 51 to 60 of about 617,408 (262)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

The use of nitrogen isotopic fractionation as a biomarker for feed conversion efficiency in pigs using blood and hair samples

open access: yesAnimal Biotechnology
This study aimed to 1) Establish relationships between feed conversion efficiency (FCE; live weight gain/intake) and several biomarkers in pigs using blood and hair samples, and 2) Investigate the relative FCE performance of pigs from maternal vs ...
Long Cheng   +7 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

open access: yesFEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page   +4 more
wiley   +1 more source

A Scoping Review on Bioethics Challenges of Conducting Clinical Research in Patients with Traumatic Brain Injury: Revisiting the Informed Consent Process

open access: yesNeuroSci
Background: Conducting research in emergency departments and critical care units is crucial for improving patient management through evidence-based practices.
Ayman El-Menyar   +2 more
doaj   +1 more source

Pro-Pluvia Rogation Ceremonies in Extremadura (Spain): Are They a Good Proxy of Winter NAO?

open access: yesAtmosphere, 2020
Rogation ceremonies are religious requests to God. Pro-pluvia rogations were celebrated during dry conditions to ask God for rain. In this work, we have recovered 37 pro-pluvia rogations from 14 documentary sources (e.g.,: ecclesiastical manuscripts ...
Nieves Bravo-Paredes   +4 more
doaj   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright   +10 more
wiley   +1 more source

Volatile Fatty Acids in Ruminal Fluid Can Be Used to Predict Methane Yield of Dairy Cows

open access: yesAnimals, 2019
The dry matter intake (DMI) of forage-fed cattle can be used to predict their methane emissions. However, many cattle are fed concentrate-rich diets that decrease their methane yield.
S. Richard O. Williams   +4 more
doaj   +1 more source

RADAR-base/radar-helm-charts: s3-proxy-0.2.0

open access: yes, 2023
A Helm chart for S3 Proxy. It uses https://hub.docker.com/r/andrewgaul/s3proxy to proxy S3 API requests to any supported cloud provider. For more examples see Find some example configurations at https://github.com/gaul/s3proxy/wiki/Storage-backend ...
Joris Borgdorff   +4 more
core   +1 more source

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