Results 51 to 60 of about 1,457,511 (283)

Predicción de tipos de cambio utilizando monedas MILA con Google Trends

Multidisciplinary Business Review, 2023
El propósito de este artículo es evaluar la capacidad predictiva que tiene la herramienta de Google Trends para predecir los tipos de cambio de los países que componen el mercado MILA: Chile, Perú, Colombia y México.
Michelle Sepúlveda, Francisca Menéndez, Nicolás Hardy Hernández, Francesca Albarracín   +3 more
doaj   +1 more source

Single proxy control

Biometrics
ABSTRACTNegative control variables are sometimes used in nonexperimental studies to detect the presence of confounding by hidden factors. A negative control outcome (NCO) is an outcome that is influenced by unobserved confounders of the exposure effects on the outcome in view, but is not causally impacted by the exposure.
Chan Park, David B Richardson, Eric J Tchetgen Tchetgen   +2 more
openaire   +3 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Impact of Seawater Inorganic Carbon Chemistry on Element Incorporation in Foraminiferal Shell Carbonate

Geochemistry, Geophysics, Geosystems
Reconstruction of the marine inorganic carbon system relies on proxy signal carriers, such as element/calcium (El/Ca) ratios in foraminiferal shells. Concentrations of boron, lithium, strontium, and sulfur have been shown to vary with carbonate system ...
S. Karancz, L. J. deNooijer, G. J. A. Brummer, J. Lattaud, N. Haghipour, Y. Rosenthal, G. J. Reichart   +6 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Checkpoint blockade and the stem‐like T cell trade‐off

Molecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source

Growth Increments of Coralline Red Alga Clathromorphum Compactum Capture Sea‐Ice Variability Links to Arctic and Atlantic Multidecadal Oscillations (1805–2015)

Geophysical Research Letters
Given sea ice's importance in global climate regulation, fully understanding the role of natural temperature and atmospheric patterns like the Arctic Oscillation (AO), North Atlantic Oscillation (NAO) and Atlantic Multidecadal Oscillation (AMO) in its ...
N. Leclerc, J. Halfar, S. Hetzinger, A. Tsay, G. W. K. Moore   +4 more
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Proxy Signature Scheme with Effective Revocation Using Bilinear Pairings [PDF]

, 2007
We present a proxy signature scheme using bilinear pairings that provides effective proxy revocation. The scheme uses a binding-blinding technique to avoid secure channel requirements in the key issuance stage.
Das, Manik Lal, Phatak, Deepak B, Saxena, Ashutosh   +2 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source