Results 31 to 40 of about 1,928,402 (253)
Most research to date has focused on understanding why states use proxies and the impact this indirect conflict strategy has had on various conflict dynamics.
Karlén, Niklas,
core
A Perfect Proxy? The United States-Syrian Democratic Forces Partnership
The US blueprint for operations in Syria included a “by, with, and through” approach to working with local proxies to fight ISIS insurgents. The approach also formed the framework for the United States–Syrian Democratic Forces partnership.
Maguire, Dylan
core +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Purpose Accurate assessment of chronic pain and functional disability in children and adolescents is imperative for guiding pain management interventions.
Joan W. Hanania +4 more
doaj +1 more source
Metrics to quantify the degree of co-location of urban water infrastructure
Co-located infrastructure networks such as road, water, and sewer in theory offer the possibility for integrated multi-infrastructure interventions. However, how closely these networks are aligned in space and time determines the practical extent to ...
Shamsuddin Daulat +4 more
doaj +1 more source
BackgroundRespiratory syncytial virus (RSV) is a major cause of respiratory infection in children. Despite usually following a consistent seasonal pattern, the 2020-2021 RSV season in many countries was delayed and changed in ...
Hersh D Ravkin +2 more
doaj +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Goodbye to Projects? - Briefing Paper 4: Lessons for the community-based planning interventions [PDF]
YesThis briefing paper compares two approaches to community-based planning in Tanzania, South Africa and Uganda. Analysing these interventions through an audit of sustainable livelihood `principles¿ (as a proxy for best practice) reveals general lessons
Muhumuza, F. +6 more
core +3 more sources
Coral skeleton P/Ca proxy for seawater phosphate: Multi-colony calibration with a contemporaneous seawater phosphate record [PDF]
A geochemical proxy for surface ocean nutrient concentrations recorded in coral skeleton could provide new insight into the connections between sub-seasonal to centennial scale nutrient dynamics, ocean physics, and primary production in the past ...
Cobb, K. M. +12 more
core +1 more source

