Results 191 to 200 of about 19,760 (270)

Data‐Driven Engineering of Thermostable Collagen‐Mimetic Peptoid Triple Helices

open access: yesMacromolecular Rapid Communications, EarlyView.
Data‐driven active learning discovery of collagen‐mimetic peptoids capable of forming a thermostable collagen‐like triple helix using computational screening followed by experimental validation. ABSTRACT Collagen‐mimetic peptides (CMPs) are engineered molecules designed to replicate the triple‐helical structure of natural collagen.
Alex Berlaga   +6 more
wiley   +1 more source

MDSGene Systematic Review of Common Forms of Dominant Hereditary Spastic Paraplegia: Novel Insights

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Hereditary spastic paraplegia (HSP) is a neurodegenerative disorder characterized by progressive spasticity and lower limb weakness. The most common forms of autosomal dominant HSP are caused by pathogenic variants in SPAST (SPG4 or HSP‐SPAST), ATL1 (SPG3A or HSP‐ATL1), and REEP1 (SPG31 or HSP‐REEP1).
Ce Kang   +24 more
wiley   +1 more source

Parkinson's‐Linked LRRK2 and GBA1 Mutations Modulate the Peripheral Immune Response to Pseudomonas aeruginosa

open access: yesMovement Disorders, EarlyView.
Abstract Background Peripheral disease mechanisms such as immune dysregulation may contribute to Parkinson's disease (PD). To investigate interactions between common PD mutations and immune responses to environmental pathogens, we studied responses to Pseudomonas aeruginosa (P.
Julian R. Mark   +8 more
wiley   +1 more source

A Novel Architecture for Mitigating Botnet Threats in AI-Powered IoT Environments. [PDF]

open access: yesSensors (Basel)
Memos VA   +4 more
europepmc   +1 more source

Accelerating MRI With Longitudinally‐Informed Latent Posterior Sampling

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To accelerate MRI acquisition by incorporating the previous scans of a subject during reconstruction. Although longitudinal imaging constitutes much of clinical MRI, leveraging previous scans is challenging due to the complex relationship between scan sessions, potentially involving substantial anatomical or pathological changes, and ...
Yonatan Urman   +4 more
wiley   +1 more source

Leveraging blockchain with zero knowledge proofs in wearable health technologies for personalized healthcare. [PDF]

open access: yesSci Rep
Khan AA   +6 more
europepmc   +1 more source

Impact of Partial Echo on 4D Flow MRI: The Insight From Synthetic MRI

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose The aim of this study is to investigate the impact of the partial echo on 4D flow MRI sequences thanks to in silico coupled MRI‐CFD (computational fluid dynamics) simulations. Methods Two sequences are studied: one with a full echo (FE) and another using partial echo (PE) with an echo symmetry fraction of 0.75.
Morgane Garreau   +6 more
wiley   +1 more source

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