Results 151 to 160 of about 159,476 (341)
Pattern Research Project: An Investigation of The Pattern And Printing Process - Bogolanfini [PDF]
, 2018 2018 Pattern Research Project Kassiah Skipwith – Bogolanfini The Pattern Research Project involves research and analysis of contemporary patterns found in the textiles and wallcoverings of the built interior environment. Patterns use motif, repetition,
Skipwith, Kassiah
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David Marsden's Comparative and Theoretical Craft: Signposts to a Better World of Work
British Journal of Industrial Relations, EarlyView.ABSTRACT David Marsden enriched and extended the field of employment relations with his interdisciplinary and comparative practice. This introduction to the special issue honouring his work examines the nature of David's contribution and analyses his influence on employment relations and adjacent fields.
Sarah Ashwin +2 more
wiley +1 more source
Evolutionary descent of prion genes from a ZIP metal ion transport ancestor [PDF]
, 2009 In the more than 20 years since its discovery, both the phylogenetic origin and cellular function of the prion protein (PrP) have remained enigmatic.
David Westaway +4 more
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Brain Pathology, EarlyView.Deep learning tissue mapping can guide region of interest selection for spatial transcriptomic analyses. Using this method, a transcriptional catalogue of focal cortical dysplasia type IIb was generated, revealing enrichment for markers of inhibitory glycinergic signaling in cytomegalic dysmorphic neurons.
Ameesha Paliwal +8 more
wiley +1 more source
Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice
Brain Pathology, EarlyView.We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga +11 more
wiley +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Biomolecular ConceptsThe negative slope of human ovulatory fidelity begins with a high follicular fund balance with gradual withdrawals over time. This depletion of reserve is a sentinel event foreshadowing severe reproductive loss and, eventually, systemic aging. Conversely,
Sills Eric Scott +6 more
doaj +1 more source
University Exams and Psychosocial Stress: Effects on Cortisol Rhythmicity in Students
Clinical Endocrinology, EarlyView.ABSTRACT Background University exams are recognised as naturalistic stressors that may elicit psychosocial and physiological responses in students. This pilot study investigated the short‐ and long‐term effects of exam‐related stress on hypothalamic–pituitary–adrenal (HPA) axis activity, focusing on cortisol production and rhythmicity.
Filipy Borghi +6 more
wiley +1 more source