Combating ageing beyond the cell: Emerging roles of extracellular proteostasis
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh +7 more
wiley +1 more source
Functions of the prp operon in carbon source metabolism and acetic acid resistance in acetic acid bacteria: a case study in Acetobacter pasteurianus CGMCC 1.41. [PDF]
Yang H, Ehrenreich A, Liebl W, Chen F.
europepmc +1 more source
ABSTRACT Aim The aim of the present systematic review is to compare the effects of manual vs. powered toothbrushes on gingival lesions. Methods Comprehensive literature searches of PubMed, Embase, Scopus, and the Cochrane Library were conducted up to May 6, 2024, to identify randomized clinical trials examining the impact of manual and powered ...
C. Molina +4 more
wiley +1 more source
Are orthobiologics a plausible therapeutic option for patello-femoral pathology? A systematic review of clinical and radiological outcomes. [PDF]
Franceschi C +8 more
europepmc +1 more source
Testing for Non‐Severe Heritable Platelet Function Disorders
ABSTRACT Heritable platelet function disorders (HPFD) are a diverse group of bleeding disorders characterised by a primary qualitative defect in platelet function rather than platelet number. HPFD may be broadly categorised according to the severity of bleeding, with Glanzmann thrombasthenia and Bernard Soulier syndrome classically considered severe ...
Kate Burley +3 more
wiley +1 more source
Outcomes of Acute Achilles Tendon Repair with Platelet-Rich Plasma Augmentation: A Comprehensive Review of Comparative Studies. [PDF]
Mercurio M +8 more
europepmc +1 more source
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra +5 more
wiley +1 more source
Functional and Return-to-Sport Outcomes After Biologic Augmentation in Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis. [PDF]
Alturki AA +8 more
europepmc +1 more source
Darier disease—A review highlighting new insights from the Darier Disease International Task Force
This review provides a global, clinically focused overview of DD, detailing cutaneous and extracutaneous manifestations, disease classification and severity scoring. It emphasizes early recognition, multidisciplinary management and practical guidance for dermatologists to apply evidence‐based care in diverse skin phototypes. Abstract Darier disease (DD)
Sofia Labbouz +49 more
wiley +1 more source
A Brief Overview and Update of Regenerative Medicine for the Treatment of Musculoskeletal Conditions. [PDF]
Negaard M, Kelleher M.
europepmc +1 more source

