Results 121 to 130 of about 83,022 (311)

Glycopolymeric nanoparticles transported by activated platelets protect ischemic myocardium by alleviating PANoptosis through targeting macrophage Dectin‐1

BMEMat, EarlyView.
NP‐SF, designed to target macrophage Dectin‐1 and activated platelets, selectively accumulated in ischemic myocardium, where it was taken up by macrophages after platelet hitchhiking. By inhibiting NLRC5‐related PANoptosis, NP‐SF significantly attenuated pathological damage, and effectively preserved cardiac function in a murine ischemia–reperfusion ...
Guanye Yu, Na Yang, Yan Zhang, Lingxin Peng, Yi Li, Yue Chao, Qinfang Miao, Haikun Qi, Jianhui Zhuang, Weixia Jian, Bingyu Li, Wenhui Peng, Jinghua Chen, Shiyu Gong   +13 more
wiley   +1 more source

Hyperbranched poly‐L‐lysine surface‐engineered bioprosthetic heart valves with anti‐calcification, anti‐infection, and durability

BMEMat, EarlyView.
The challenges of bioprosthetic heart valves (BHV) with respect to calcification, infection, and poor durability are tackled by surface engineering of hyperbranched poly‐L‐lysine (HBPL), providing a translational solution to improve long‐term valve performance.
Pai Peng, Dongchao Qiu, Yongyuan Kang, Qiaoxuan Wang, Xuelong Wang, Boyana Parvanova, Miroslav Karabaliev, Changyou Gao   +7 more
wiley   +1 more source

How Can Eco‐Friendly Products Be Marketed Effectively? Evidence From a Multinational Study on the Intention–Behaviour Gap for Smartphones Made With Eco‐Friendly Substitute Materials

Business Strategy and the Environment, EarlyView.
ABSTRACT As global environmental concerns intensify, firms are increasingly expected to embed environmental responsibility into their core strategies. However, uncertainty remains over whether eco‐friendly initiatives are economically rewarded, reflecting ambiguity in consumers' true environmental preferences.
Kimitaka Nishitani, Eri Nakamura, Fumikazu Morimura, Yumi Nakamori, Tsugio Watanabe, Daisuke Furuta, Tomoya Mizuta   +6 more
wiley   +1 more source

Entropy and mechanistic concepts after intraovarian platelet-rich plasma: Experimental considerations for local tissue responses mediated by NF-κB and TNF-α

Biomolecular Concepts
The negative slope of human ovulatory fidelity begins with a high follicular fund balance with gradual withdrawals over time. This depletion of reserve is a sentinel event foreshadowing severe reproductive loss and, eventually, systemic aging. Conversely,
Sills Eric Scott, Harrity Conor, Chu Howard I., Wang Jing-Wen, Yang Fan, Tan Seang Lin, Wood Samuel H.   +6 more
doaj   +1 more source

Evaluating the Efficacy of Platelet-Rich Plasma (PRP) in Accelerating Healing and Reducing Complications in Oral Surgery

Journal of Pharmacy and Bioallied Sciences
Background: The process of curing and regaining the integrity of damaged tissues is known as healing. An autologous concentration of platelets embedded in plasma is known as platelet-rich plasma (PRP).
Liza Mohanty, Abhishek Harish, Sachin B. Mangalekar, Ankur Jethlia, Honey Lunkad, Jessica Y. Jeevitha, Ramanpal S. Makkad   +6 more
doaj   +1 more source

Vitiligo et phénomène de Koebner suite à des injections de plasma riche en plaquettes

The Pan African Medical Journal, 2019
Le vitiligo est un trouble commun et acquis de la pigmentation cutanée caractérisé par une perte sélective et souvent continue de mélanocytes épidermiques.
Mouna Ejjiyar, Mehdi Sahibi, Mehdi El Gueouatri, Abdelkoddous Bhihi, Mehdi Mahrouch, Imane Yafi, Moulay Driss El Amrani, Yassine Benchamkha   +7 more
doaj   +1 more source

Localized Prostate Cancer Therapy: Tumor Microenvironment‐Activated Spermine Hydrogel With Real‐Time Autonomous Fluorescence Sensing

Chemistry – A European Journal, EarlyView.
First tumor microenvironment (TME)‐responsive spermine‐loaded hydrogel with autonomous sensing for advanced local therapy of prostate cancer (PCa) is developed. Spermine can be released from the hydrogel to kill the prostate cancer cells specifically under acidic TME.
Ho‐Fai Chau, Wing‐Sze Tam, Gengguo Deng, Yik Hoi Yeung, Christine Yim Ping Wong, Ka Lo Cheng, Zhengxiao Liu, Lijia Yao, Yi Wang, Angelo H. All, Chi‐Fai Ng, Jinming Di, Ka‐Leung Wong   +12 more
wiley   +1 more source

Folding and fibril formation of prions [PDF]

Prions diseases are a group of fatal neurodegenerative disorders called the transmissible spongiform encephalopathies (TSEs), which include bovine spongiform encephalopathy in cattle, scrapie in sheep and Creutzfeldt-Jakob disease (CJD) in humans ...
Gierusz, Leszek A.
core  

Prion degradation pathways: Potential for therapeutic intervention [PDF]

, 2015
Prion diseases are fatal neurodegenerative disorders. Pathology is closely linked to the misfolding of native cellular PrP(C) into the disease-associated form PrP(Sc) that accumulates in the brain as disease progresses. Although treatments have yet to be
McKinnon, C, Tabrizi, SJ, Goold, R
core  

Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta

Clinical Pharmacology &Therapeutics, EarlyView.
Solute carriers (SLC) and ATP‐binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Although fetal sex influences placental development and function, its impact on transporter expression is unclear.
Elijah Marsh Jung, Nicholas Ieronimakis, Bothaina Mousa, Emily D. Sheikh, Sarah E. Ligon, Joshua W. Monson, Jennifer R. Damicis, Hillary J. Kinsman, Lydia E. Bettridge, Samuel L.M. Arnold, Edward J. Kelly, Jashvant D. Unadkat, Joanne Wang   +12 more
wiley   +1 more source