Results 101 to 110 of about 153,463 (312)

Obraz chłopa i wsi w wybranych filmach polskich z lat 1968–1990 o tematyce współczesnej

open access: yesŚląski Kwartalnik Historyczny Sobótka
The article analyses the motif of the countryside in films made during the last two decades of the Polish People’s Republic, focusing on contemporary plots of the era.
Radosław Domke
doaj   +1 more source

Gerstmann-Sträussler-Scheinker disease revisited: accumulation of covalently-linked multimers of internal prion protein fragments [PDF]

open access: yes, 2019
Despite their phenotypic heterogeneity, most human prion diseases belong to two broadly defined groups: Creutzfeldt-Jakob disease (CJD) and Gerstmann-Sträussler-Scheinker disease (GSS).
Cali, Ignazio   +8 more
core   +1 more source

Flavour Ester Synthesis by Immobilized Lipases: A Research Overview With Industrial Relevance

open access: yesFlavour and Fragrance Journal, EarlyView.
Research landscape of flavour ester synthesis by immobilized lipases, highlighting enzymatic routes, major research themes and aspects related to industrial relevance, including enzyme reuse, solvent‐free systems, process intensification and scale‐up potential.
Nicole Marasca   +3 more
wiley   +1 more source

Research on the preventive and reparative mechanisms of platelet-rich plasma-biodegradable quick setting spray for solar dermatitis

open access: yesZhongguo shuxue zazhi
[Objective] To investigate the preventive and reparative mechanisms of platelet-rich plasma-biodegradable quick setting spray (PRP-BQSS) on solar dermatitis, thereby providing a safe and effective novel therapeutic approach for clinical application ...
ZHU Zhanhong   +4 more
doaj   +1 more source

Molecular dynamics as an approach to study prion protein misfolding and the effect of pathogenic mutations [PDF]

open access: yes, 2011
Computer simulation of protein dynamics offers unique high-resolution information that complements experiment. Using experimentally derived structures of the natively folded prion protein (PrP), physically realistic dynamics and conformational changes ...
Daggett, Valerie, van der Kamp, Marc W
core   +2 more sources

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon   +5 more
wiley   +1 more source

Molecular Dynamics Studies on 3D Structures of the Hydrophobic Region PrP(109-136) [PDF]

open access: yes, 2013
Prion diseases caused by the conversion from a soluble normal cellular prion protein into insoluble abnormally folded infectious prions, are invariably fatal and highly infectious degenerative diseases that affect a wide variety of mammalian species. The
Zhang, Jiapu, Zhang, Yuanli
core   +4 more sources

Tales From Within: Dental Students’ Reflective Activities Involving Equity‐Deserving Communities

open access: yesJournal of Dental Education, EarlyView.
ABSTRACT Objective Undergraduate dental training benefits from community service‐learning (CSL) placements, in which equity‐deserving groups receive oral health care and students can critically reflect on their experiences. This study aimed to thematically explore the moments of revelation and struggle that senior dental students reflected on while ...
Mario Brondani   +2 more
wiley   +1 more source

Targeting of the prion protein to the cytosol: mechanisms and consequences

open access: yes, 2010
Prion diseases are characterized by the conformational transition of the cellular prion protein (PrPC) into an aberrant protein conformer, designated scrapie-prion protein (PrPSc).
Miesbauer, M.   +3 more
core  

Structural modeling and functional analysis of the essential ribosomal processing protease Prp from Staphylococcus aureus [PDF]

open access: yes, 2017
In Firmicutes and related bacteria, ribosomal large subunit protein L27 is encoded with a conserved N-terminal extension that is removed to expose residues critical for ribosome function. Bacteria encoding L27 with this N-terminal extension also encode a
Christie, Gail E.   +3 more
core   +2 more sources

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