Results 291 to 300 of about 159,476 (341)
Pathogenic Gαo Mutants Drive Dominant GPCR Coupling in GNAO1 Encephalopathies
Mutations in GNAO1, the gene encoding Gαo, are associated with a wide range of neurodevelopmental disorders. In this study, we show that Gαo variants linked to the most severe patient phenotypes fail to disengage from activated Gi/o‐coupled GPCRs, thereby blocking GRK‐mediated receptor phosphorylation and internalization.
Yonika A. Larasati +4 more
wiley +1 more source
The Effectiveness of Platelet-Rich Plasma in the Management of Rotator Cuff Tears: A Systematic Review and Meta-Analysis. [PDF]
Rout S, Rout S.
europepmc +1 more source
Tissue Engineering: Oromaxillofacial reconstruction with platelet rich plasma (PRP)
Arash Poorsattar-Bejehmir
openalex +1 more source
Small‐diameter vascular grafts with compliance tunable by design are fabricated via melt electrowriting. By controlling the winding angle of intertwined helical fibers, grafts with compliances matching those of human vessels, from veins to arteries, are realized. This holds the potential of avoiding a compliance mismatch, which has been identified as a
Kilian Maria Arthur Mueller +8 more
wiley +1 more source
PRP-loaded pH-responsive hydrogel for the amelioration of ventricular remodeling following myocardial infarction. [PDF]
Liu JE +10 more
europepmc +1 more source
A robust heparin‐mimicking coating based on sulfated polyglycerol is constructed via layer‐by‐layer assembly on bloodcontacting surfaces. The coating exhibits long‐term anticoagulant and anti‐inflammatory properties by resisting protein adsorption, preventing platelet activation, and suppressing immune responses, offering a promising strategy for ...
Kunpeng Liu +3 more
wiley +1 more source
Efficacy of Platelet Rich Plasma Versus Placebo for Improvement in Olfactory Function in Adults With Olfactory Dysfunction: A Systematic Review and Meta-Analysis. [PDF]
Jafar AB +4 more
europepmc +1 more source
A biomaterial combining fresh platelet‐rich plasma with freeze‐dried chitosan (CS‐PRP) enhances diabetic skin wound healing in rats. CS‐PRP accelerates closure over the course of a month, improves healing tissue architecture and collagen remodeling, and sustains vascularization.
Laura Ahunon +5 more
wiley +1 more source
Effects of platelet-rich plasma gel on vaginal microecology and stump healing and its underlying mechanism. [PDF]
Wang M +5 more
europepmc +1 more source
Molybdenum (Mo), with its unique strength, uniform corrosion, and radiopacity, enables innovative biodegradable implants for transformative stroke therapy. Abstract Neurovascular implants for stroke intervention face a critical dilemma: permanent devices (e.g., nitinol stents, platinum coils) often trigger chronic inflammation and recurrence, whereas ...
Yunong Shen +11 more
wiley +1 more source

