Results 1 to 10 of about 51,239 (287)
Scientific Reports, 2021 (Pro)renin receptor (PRR) and Yes-associated protein (YAP) play an important role in cardiovascular diseases. However, the role of PRR–YAP pathway in the pathogenesis of DCM is also not clear. We hypothesized that PRR–YAP pathway may promote pathological
Shiran Yu +7 more
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Frontiers in Physiology, 2021 Diabetic cardiomyopathy (DCM) is a common complication associated with diabetes. The (pro)renin receptor (PRR) is an important member of the local tissue renin-angiotensin system and plays a vital role in many cardiovascular diseases.
Jie Xiong +12 more
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Comparative Safety of GLP-1 Receptor Agonists Across Gastrointestinal, Renal and Pancreatic Systems [PDF]
PharmaceuticalsObjectives: to assess the safety profile of Gastrointestinal (GIT), renal, and pancreatic effects of GLP-1 and dual receptor agonists. Methods: Disproportionality analyses were performed on FDA Adverse Event Reporting System (FAERS) data following each ...
Hala Shokr, Mohamed Mekkawy, Ali Hindi
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PRR enhances anti-tumor immunity and suppresses colitis by promoting the development and survival of naive T and iNKT cells [PDF]
Frontiers in ImmunologyThe (pro)renin receptor (PRR) is a multifunctional transmembrane protein that enhances β-catenin/TCF1 signaling and V-ATPase-mediated lysosomal acidification.
Akihiro Shimba +9 more
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West European Politics, 2023 Following the Russian full-scale invasion of Ukraine in 2022, the ‘democratic backslider’ parties in Hungary (Fidesz) and Poland (Law and Justice) took differing stances on Russia, bringing their positions on the Rule of Law (RoL) conflict and within the
Adam Holesch, P. Zagórski
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International Journal of Molecular Sciences, 2021 Oxidative stress is a major contributor to the pathogenesis of various inflammatory diseases. Accumulating evidence has shown that oxidative stress is characterized by the overproduction of reactive oxygen species (ROS). Previous reviews have highlighted
Pengwei Li, M. Chang
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International Journal of Molecular Sciences, 2022 Cell-surface-localized pattern recognition receptors (PRRs) and intracellular nucleotide-binding domain and leucine-rich repeat receptors (NLRs) are plant immune proteins that trigger an orchestrated downstream signaling in response to molecules of ...
C. Ramírez-Zavaleta +4 more
semanticscholar +1 more source
Overweight and obesity in south central Uganda: A population-based study.
PLOS Global Public Health, 2022 Obesity is a rapidly growing global health challenge, but there are few population-level studies from non-urban settings in sub-Saharan Africa. We evaluated the prevalence of overweight (body mass index (BMI)>25 kg/m2), obesity (BMI>30 kg/m2), and ...
Adeoluwa Ayoola +14 more
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New Phytologist, 2022 Heterodimeric complexes incorporating the lipase-like proteins EDS1 with PAD4 or SAG101 are central hubs in plant innate immunity. EDS1 functions encompass signal relay from TIR domain-containing intracellular NLR-type immune receptors (TNLs) towards ...
Josua Zönnchen +12 more
semanticscholar +1 more source
Cellular and Molecular Gastroenterology and Hepatology, 2021 Background & Aims: Activation of the (pro)renin receptor (PRR) up-regulates the expression of profibrotic genes in the kidney and heart. We aimed to investigate the role of PRR in hepatic fibrogenesis.
Yun-Cheng Hsieh +10 more
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