Results 221 to 230 of about 55,351 (255)

From Proteinopathy to Immunopathy in Alzheimer's Disease-A Role for Astrocytic Calcineurin? [PDF]

J Neurochem
Lim D, Tapella L.
europepmc   +1 more source

Distribution of Big Tau Isoforms in the Human Central and Peripheral Nervous System

Annals of Neurology, Volume 100, Issue 4, Page 709-736, October 2026.
Objective Tau is widely studied in neurodegeneration, yet most work has focused on canonical brain tau isoforms. A longer isoform, “big tau,” produced by inclusion of exon 4a, is expressed in the peripheral nervous system (PNS) and central nervous system (CNS) regions.
Rama Krishna Koppisetti, Nicolas R. Barthélemy, Kanta Horie, Cindy V. Ly, Kaleigh F. Roberts, Srinivas Koutarapu, Richard J. Perrin, Erin E. Franklin, Chiara Pedicone, Joshua Orrick, Justin Melendez, Timothy M. Miller, Chihiro Sato, Nupur Ghoshal, Alison M. Goate, Celeste M. Karch, Randall J. Bateman, Soumya Mukherjee   +17 more
wiley   +1 more source

Extracellular Vesicles from <i>Candida albicans</i> and <i>Aspergillus fumigatus</i> Differentially Integrate PRR and cGAS-STING Signaling to Shape Macrophage Responses. [PDF]

J Fungi (Basel)
Froldi JL, Piraine REA, Tavares LA, Nogueira LFB, Santos P, Almeida F.   +5 more
europepmc   +1 more source

Axial Connectivity of the Lung Microbiome: A Review of Interorgan Crosstalk

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
The human microbiome mediates immune homeostasis and metabolic signaling across organs. Beyond the gut‐lung axis, crosstalk between the lung and other organ systems is less recognized. This review assesses the axial connectivity of the lung microbiome across the gut, brain, skin, heart, kidney, and liver.
Mathangi Palanivel, Jayanth Kumar Narayana, Sanjay H. Chotirmall   +2 more
wiley   +1 more source

Engineering PRRs: A new path to durable resistance. [PDF]

aBIOTECH
Wang D, Li Z, Yang W, Que Y, Chang M.
europepmc   +1 more source

Anti‐inflammatory and cytotoxic properties of kānuka (Kunzea ericoides) subcritical water extract

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 10, Page 2072-2084, October 2026.
Abstract BACKGROUND Kānuka (Kunzea ericoides) is a medicinal plant native to New Zealand with numerous therapeutic benefits due to its rich bioactive profile. Although several in vitro studies have shown promising anti‐inflammatory activity, substantial evidence elucidating its underlying inflammatory regulatory mechanism and evaluating its cytotoxic ...
Indhuja Devadass, Simon Swift, Saeid Baroutian   +2 more
wiley   +1 more source

Post‐Tuberculosis Lung Disease: Clinicopathologic Insights, Diagnosis, Prevention, and Management

MedComm, Volume 7, Issue 10, October 2026.
A comprehensive review on post‐tuberculosis lung disease (PTLD) addresses the epidemiology, pathogenesis, clinical phenotypes and management, risk factors, prevention and systems approach, and future directions. This review provides standardized definitions, mechanistic insights and biomarkers of PTLD development, and clinical strategies for PTLD ...
Radha Gopalaswamy, Selvakumar Subbian
wiley   +1 more source

The applicability of pig oral fluid in laboratory diagnostics of porcine reproductive and respiratory syndrome and its effectiveness in controlled exposure of gilts. [PDF]

Front Vet Sci
Plut J, Brabec M, Štukelj M.
europepmc   +1 more source

Establishment of an Indirect ELISA Detection Method for Porcine Reproductive and Respiratory Syndrome Virus NSP10. [PDF]

Vet Sci
Li G, Zhang Q, Chen X, Li H, Wang R, Zhang K, Ye Y, Zhao M.   +7 more
europepmc   +1 more source

T cell-intrinsic PRR signaling in immunity and pathology. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Shi Y, Wang M, Dai B, Lu X, Li S.
europepmc   +1 more source