Results 51 to 60 of about 55,281 (296)
Pattern-recognition receptors in endometriosis: A narrative review
Frontiers in Immunology, 2023 Endometriosis is closely associated with ectopic focal inflammation and immunosuppressive microenvironment. Multiple types of pattern recognition receptors (PRRs) are present in the innate immune system, which are able to detect pathogen-associated ...
Bao Guo +7 more
doaj +1 more source
Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Advanced Science, EarlyView.Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
Viable porcine arteriviruses with deletions proximal to the 3 ' end of the genome [PDF]
, 2001 In order to obtain attenuated live vaccine candidates of porcine reproductive and respiratory syndrome virus (PRRSV), a series of deletions was introduced at the 3′ end of the viral genome using an infectious cDNA clone of the Lelystad virus isolate. RNA
Rottier, P.J.M. +3 more
core
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Advanced Science, EarlyView.Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
The impact of innate immune response on the efficacy of oncolytic viruses
Вопросы вирусологииOncolytic viruses represent a promising class of immunotherapeutic agents for the treatment of malignant tumors. The proposed mechanism of action of various oncolytic viruses has initially been explained by the ability of such viruses to selectively lyse
Kirill N. Trachuk +3 more
doaj +1 more source
A Porcine Myelomonocytic Cell Line, 3D4/31 is Susceptible to PRRSV Infection in vitro [PDF]
, 2006 PRRS virus has been characterized into two genotypes, North American (NA) and European (EU). It has been reported that MA-104 and Marc-145 cells were the only permissive continuous cell lines to PRRS virus infection where the EU PRRS virus required ...
Li, VYY, Wong, CKW, Leung, FCC, MA, CM
core
Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants
Advanced Science, EarlyView.The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann +11 more
wiley +1 more source
BMC Genomics, 2017 Background The WUR1000125 (WUR) single nucleotide polymorphism (SNP) can be used as a genetic marker for host response to porcine reproductive and respiratory syndrome (PRRS), PRRS vaccination, and co-infection with porcine circovirus type 2b (PCV2b ...
Jenelle R. Dunkelberger +8 more
doaj +1 more source
Advanced Science, EarlyView.A fully synthetic four‐component vaccine has been developed combining Tn antigen, vizantin (Mincle agonist), rhamnose (antibody recruitment), and mannose (CD206 targeting). By synergistically activating Mincle, FcγR, and CD206 pathways, it elicits strong IgG switching and cytotoxic T‐cells, significantly inhibiting tumors in mice.
Wenbo Ming +9 more
wiley +1 more source
, 2022 Spatial distribution of reported PRRS cases (2012–2014), and simulated PRRS cases for a high and a low virulent strain.
Pablo Valdes-Donoso (2146567) +1 more
core +1 more source