Results 221 to 230 of about 343,225 (391)

Spatial Transcriptomic Analysis Reveals HDAC Inhibition Modulates Microglial Dynamics to Protect Against Ischemic Stroke in Mice

open access: yesGlia, EarlyView.
Spatial transcriptomic analysis unravels the mechanisms by which HDACi ameliorates neuroinflammation and enhances neuroprotection by modulating the expression of microglial transcriptomes in the ischemic mouse brain. ABSTRACT Ischemic stroke significantly contributes to global morbidity and disability through a cascade of neurological responses ...
Kevin Jayaraj   +5 more
wiley   +1 more source

Pathways to Progressive Disability in Multiple Sclerosis: The Role of Glial Cells in Chronic CNS Inflammation

open access: yesGlia, EarlyView.
ABSTRACT Multiple sclerosis (MS) is the most common non‐infectious inflammatory CNS disease, characterized by progressive neurodegeneration and focal demyelinated lesions. Traditionally considered an autoimmune disease, MS is driven by the immune system's attack on CNS myelin, resulting in cumulative disability.
Volker Siffrin
wiley   +1 more source

Dynamic spatio-temporal pruning for efficient spiking neural networks. [PDF]

open access: yesFront Neurosci
Gou S   +7 more
europepmc   +1 more source

Dormant Pruning Influence on Auxin, Gibberellin, and Cytokinin Levels in Apple Trees [PDF]

open access: hybrid, 1984
Maria Grochowska   +4 more
openalex   +1 more source

Research progress of neurovascular units involved in ischemic stroke

open access: yesIbrain, EarlyView.
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang   +4 more
wiley   +1 more source

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