Results 171 to 180 of about 118,288 (291)

Focused Ultrasound for the Treatment of Circuit and Molecular Pathology in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Focused ultrasound is rapidly emerging as a novel technology for the development of symptomatic therapies and supporting disease‐modifying treatments for Parkinson's disease (PD). At the forefront of this development is thermoablation using high‐intensity focused ultrasound, an incisionless treatment that has been extensively tested in ...
Rikke Hahn Kofoed   +7 more
wiley   +1 more source

An Open‐Label Phase 1b Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of ANX005 in Patients with Huntington's Disease

open access: yesMovement Disorders, EarlyView.
Complement activation is implicated in Huntington's disease; ANX005 is a potent inhibitor of component C1q. ANX005 exhibited a generally manageable safety profile with rapid reduction in C1q in the cerebrospinal fluid. Functional ability on composite Unified Huntington's Disease Rating Scale and total functional capacity was maintained, with potential ...
Rajeev Kumar   +15 more
wiley   +1 more source

Interpretable Machine Learning Predicting Coercivity of Sm‐Co‐Based Alloys

open access: yesMaterials Genome Engineering Advances, EarlyView.
A physically interpretable machine learning approach for predicting coercivity of Sm‐Co‐based alloys was proposed in this study. Key physical features governing coercivity were identified and reconstructed establishing a high‐throughput model for dopant screening with exceptional accuracy.
Guojing Xu   +5 more
wiley   +1 more source

Clinically Feasible White Matter Fiber Tractography in Peritumoral Zones With Cerebral Vasogenic Edema

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose In diffusion MRI, vasogenic edema manifests as a major fraction of isotropic water that dilutes the anisotropic intra‐axonal portion of the signal. Many tractography algorithms mistake vasogenic edema for the white matter boundary and terminate tracking to prevent producing spurious streamlines.
Patryk Filipiak   +6 more
wiley   +1 more source

Optimal control of pruning leaves based on GreenLab [PDF]

open access: yes, 2010
Cournède, Paul-Henry   +3 more
core  

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