PIEZO1 channels in cutaneous free nerve endings: novel insights into itch-scratch-mechanisms
Manuel Pedro Pereira +2 more
doaj +1 more source
ABSTRACT Skin changes such as xerosis and pruritus are common complications among diabetes patients and may lead to serious adverse events such as diabetic foot syndrome and amputations. Evidence suggests that daily application of optimal skincare, including gentle cleansers and moisturizers, may help improve skin barrier function, preventing ...
Robert S. Kirsner +5 more
wiley +1 more source
Have We Just Scratched the Surface? A Narrative Review of Uremic Pruritus in 2020
Purpose of review: Uremic pruritus is a highly prevalent and debilitating symptom in patients with chronic kidney disease (CKD) and end-stage kidney disease (ESKD).
Claire E. Martin +3 more
doaj +1 more source
Naltrexone: a Novel Approach to Pruritus in Polycythemia Vera [PDF]
Newsha Nikzad
openalex +1 more source
CAQ Corner: Immune‐mediated complications
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley +1 more source
Dupilumab for bullous pemphigoid with intractable pruritus [PDF]
Bullous pemphigoid (BP) is an autoimmune blistering disorder that predominantly affects the elderly. Treatment regimens typically include topical and systemic immunosuppressive medications.
Eichenfield, Dawn Z +2 more
core
Long-term safety and efficacy of trifarotene 50 μg/g cream, a first-in-class RAR-γ selective topical retinoid, in patients with moderate facial and truncal acne. [PDF]
BackgroundTreatment for both facial and truncal acne has not sufficiently been studied.ObjectivesTo evaluate the long-term safety and efficacy of trifarotene in both facial and truncal acne.MethodsIn a multicentre, open-label, 52-week study, patients ...
Ahmad, F +11 more
core
Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis. [PDF]
Chronic itch remains a highly prevalent disorder with limited treatment options. Most chronic itch diseases are thought to be driven by both the nervous and immune systems, but the fundamental molecular and cellular interactions that trigger the ...
Barton, Gregory M +11 more
core +1 more source
Hell's Itch: An Acute Reaction to Sunburn Exposure
ABSTRACT Hell's itch is a neurocutaneous dysesthesia following sunburn that is underreported in scientific literature despite considerable discussion online. ‘Hell's itch’ describes an acute, uncontrollable itch with intense stabbing pain several days post‐sunburn and often follows an inciting event such as water exposure.
Colin Kelly +2 more
wiley +1 more source
Reversal of epidural morphine-induced respiratory depression and pruritus with nalbuphine [PDF]
John Penning +2 more
openalex +1 more source

