Adult-onset perianal Langerhans cell histiocytosis presenting as pruritus ani: a case report and review of the literature [PDF]
Journal of Medical Case Reports, 2021 Background Langerhans cells belong to the histiocytic system and give rise to two tumors: Langerhans cell histiocytosis and Langerhans cell sarcoma. Clinical aggressiveness and degree of atypia distinguish the two neoplasms. Langerhans cell histiocytosis
Marah Hamdan, Jesse C. Qiao, Vid Fikfak
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SOOTHER TRIAL: Observational study of an over-the-counter ointment to heal anal itch [PDF]
Frontiers in Medicine, 2022 IntroductionPruritus ani, or rectal or anal itch, is a common perianal disorder that affects ~5% of the population of the developed world. Treatments for this disorder are somewhat limited and include conservative non-medical perianal hygiene care, and ...
Isaac Felemovicius +3 more
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Evaluation, management and future perspectives of anal pruritus: a narrative review [PDF]
European Journal of Medical Research, 2023 Purpose The without a time limitation. Most recent search was performed on 1st June 2022. Results Thorough history and physical examination are very important in view of multiple possible causes of anal pruritus.
Matas Jakubauskas, Audrius Dulskas
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Mechanism of medical hemorrhoid gel in relieving pruritus ani via inhibiting the activation of JAK2/STAT3 pathway [PDF]
Frontiers in MedicineBackgroundPruritus ani (PA), a neurofunctional dermatosis, is one of the most common complications of hemorrhoids, which seriously affects the quality of life of patients.
Zhongzhu Ai +6 more
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Anal Pruritus: Diagnosis and Management
World Journal of Colorectal Surgery, 2023 Pruritus ani is a condition that results in itching or burning in the perianal area. It can be due to primary or secondary causes and can be self-limiting or persistent.
Daniel T. Slagle, William J. Harb
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Pruriplastic Itch—A Novel Pathogenic Concept in Chronic Pruritus
Frontiers in Medicine, 2021 The International Association for the Study of Pain (IASP) defined three descriptors for pain: nociceptive pain is “pain that arises from actual or threatened damage to non neural tissue and is due to the activation of nociceptors”; neuropathic pain is ...
Laurent Misery
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Turkish Journal of Colorectal Disease, 2021 Pruritus Ani is one of the common dermatological diseases of the perianal skin in the general population. This disease affects 1%-5% of the society. It presents as itching and burning in the perianal area. Men are affected four times more than women, and
Ahmet Topçu +4 more
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Anogenital Pruritus – An Overview [PDF]
Journal of Clinical and Diagnostic Research, 2016 Anogenital pruritus is defined as intense itching, acute or chronic, affecting the anal, perianal, perineal and genital skin, which is a dominant problem in the course of various cutaneous and systemic conditions.
Murugan Swamiappan
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Recalcitrant anal and genital pruritus treated with dupilumab
International Journal of Women's Dermatology, 2018 Chronic anogenital pruritus can significantly impair affected patients’ quality of life by disrupting their sleep, mood, sexual function, and personal relationships.
E.J. Yang, BS, J.E. Murase, MD
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High prevalence of scrapie in a dairy goat herd: tissue distribution of disease-associated PrP and effect of PRNP genotype and age [PDF]
, 2009 Following a severe outbreak of clinical scrapie in 2006–2007, a large dairy goat herd was culled and 200 animals were selected for post-mortem examinations in order to ascertain the prevalence of infection, the effect of age, breed and PRNP genotype on
Dawson, M. +13 more
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