Results 31 to 40 of about 4,474 (234)

Model‐informed drug development to support nemolizumab clinical development in adults and adolescents with moderate to severe atopic dermatitis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Population pharmacokinetic (popPK) and pharmacokinetic‐pharmacodynamic (PK/PD) models were developed to support clinical development of nemolizumab, a humanized monoclonal antibody targeting the IL‐31 receptor α, in adolescents and adults with moderate‐to‐severe atopic dermatitis (AD).
Floris Fauchet   +17 more
wiley   +1 more source

Human Extensive Head Skin Myiasis [PDF]

open access: yesIranian Journal of Public Health, 2009
"nChrysomya bezziana Villeneuve is the most important fly, which produces myiasis, exists as an obligate ectoparasite in the ani­mals, and afflicts human.
M Soleimani Ahmadi   +3 more
doaj  

More Than a Question of Correlation: Characterization of the Evidentiary Basis for Biomarker Surrogates Used in European Marketing Authorizations

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Traditionally, clinical outcomes measuring how a patient feels, functions, or survives are preferred endpoints in clinical trials; however, some may take a long time to manifest in slowly developing diseases. Biomarkers, if properly validated, can serve as surrogate endpoints, acting as substitutes for clinical outcomes.
Renske Johanna Grupstra   +4 more
wiley   +1 more source

Świąd odbytu – etiologia i metody terapii

open access: yesPrzegląd Dermatologiczny, 2011
Perianal pruritus is an unpleasant cutaneous sensation that inducesscratching of the skin around the anal orifice. It is a common symptomin the course of many systemic, dermatological and proctological disorders.The diagnosis of pruritus ani may be ...
Karolina Hadasik   +2 more
doaj  

Oral Myiasis: a review [PDF]

open access: yes, 2011
Myiasis is the infestation of tissues, organs of living vertebrate, animals and humans by certain dipterans fly larvae which feed on the host’s tissues and body fluids, often causing extensive damage to the host tissues if left untreated. Oral Myiasis
Aggarwal, Amit   +5 more
core   +1 more source

CAQ Corner: Immune‐mediated complications

open access: yes, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Metileno mėlio tirpalo injekcija į išangės srities odą idiopatiniam niežuliui gydyti

open access: yesLietuvos Chirurgija, 2005
Narimantas Evaldas Samalavičius1, Tomas Poškus2, Alfredas Kilius1 1 Vilniaus universiteto Onkologijos instituto Chirurgijos klinika, Santariškių g.
Narimantas Evaldas Samalavičius   +2 more
doaj  

ABC of sexually transmitted infections - Main presentations of sexually transmitted infections in men [PDF]

open access: yes, 2004
This article is adapted from the fifth edition of the ABC ofSexually Transmitted Diseases, which is published by BMJBooks (www.bmjbooks.com).Some sexually transmitted infections, such as gonorrhoea and chlamydial infection, have different presentations ...
Richens, J
core  

Satisfactory safety and immunogenicity of MSP3 malaria vaccine candidate in Tanzanian children aged 12–24 months [PDF]

open access: yes, 2009
BACKGROUND: Development and deployment of an effective malaria vaccine would complement existing malaria control measures. A blood stage malaria vaccine candidate, Merozoite Surface Protein-3 (MSP3), produced as a long synthetic peptide, has been shown ...
Acleus Rutta   +14 more
core   +2 more sources

Real‐world progression‐free survival and overall survival in patients with HR+/HER2− advanced breast cancer treated in first‐line with ribociclib, endocrine monotherapy or chemotherapy: Results from the observational RIBANNA study

open access: yesInternational Journal of Cancer, EarlyView.
What's New? The CDK4/6 inhibitor ribociclib in combination with an endocrine‐based therapy has demonstrated significant progression‐free and overall survival benefits in patients with advanced/metastatic HR+/HER2‐ breast cancer in the pivotal MONALEESA trials.
Peter A. Fasching   +20 more
wiley   +1 more source

Home - About - Disclaimer - Privacy