Results 161 to 170 of about 65,404 (216)
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The IBD and PSC Phenotypes of PSC-IBD
Current Gastroenterology Reports, 2018To review the characteristics of IBD and PSC that occur in association, as well as their reciprocal influences on disease evolution, in adult and pediatric populations.IBD co-existing with PSC is genetically and clinically distinct from IBD alone. It is frequently characterized by pancolitis, rectal sparing, and possibly backwash ileitis, as well as a ...
Amanda Ricciuto +2 more
exaly +3 more sources
Current Hepatology Reports, 2020
Overlap syndromes show concomitant or sequential findings of two or more autoimmune liver diseases. Primary sclerosing cholangitis (PSC) is rare and PSC-overlap syndromes are much rarer. There is limited data in PSC-overlap syndromes which pose significant diagnostic and therapeutic challenges for this condition.
Nathalie Pena Polanco +2 more
exaly +2 more sources
Overlap syndromes show concomitant or sequential findings of two or more autoimmune liver diseases. Primary sclerosing cholangitis (PSC) is rare and PSC-overlap syndromes are much rarer. There is limited data in PSC-overlap syndromes which pose significant diagnostic and therapeutic challenges for this condition.
Nathalie Pena Polanco +2 more
exaly +2 more sources
Best Practice & Research Clinical Gastroenterology, 2001
Primary sclerosing cholangitis (PSC) does not exhibit simple Mendelian inheritance attributable to a single gene locus and our knowledge of the genetics of this complex disease is based entirely on case-control studies of candidate genes. The prime candidates in PSC are inherited variation (polymorphism) in the genes that regulate the immune response ...
Donaldson PT, Norris S
openaire +3 more sources
Primary sclerosing cholangitis (PSC) does not exhibit simple Mendelian inheritance attributable to a single gene locus and our knowledge of the genetics of this complex disease is based entirely on case-control studies of candidate genes. The prime candidates in PSC are inherited variation (polymorphism) in the genes that regulate the immune response ...
Donaldson PT, Norris S
openaire +3 more sources
Will we ever model PSC? – “It's hard to be a PSC model!”
Clinics and Research in Hepatology and Gastroenterology, 2011Cholangiopathies such as primary sclerosing cholangitis (PSC) represent an important group of liver diseases of the intra- and extrahepatic bile ducts frequently causing end-stage liver disease with significant morbidity and mortality due to limited treatment options. The relatively low incidence of PSC and the difficult accessibility of the human bile
Marion J, Pollheimer +2 more
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Theoretical and Applied Genetics, 1978
Mean PSC increased following each generation of recurrent selection in F1, F2 and F3 Nemesia strumosa families derived from a cross of a 100% PSC plant to an unrelated 0% PSC plant. The first 100% PSC individuals occurred in the F4. Populations derived through sib pollination tended to have higher PSC means than lines derived through self pollination ...
C D, Robacker, P D, Ascher
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Mean PSC increased following each generation of recurrent selection in F1, F2 and F3 Nemesia strumosa families derived from a cross of a 100% PSC plant to an unrelated 0% PSC plant. The first 100% PSC individuals occurred in the F4. Populations derived through sib pollination tended to have higher PSC means than lines derived through self pollination ...
C D, Robacker, P D, Ascher
openaire +2 more sources
Autoimmune Hepatitis and PSC Connection
Clinics in Liver Disease, 2008This article describes the connection between autoimmune hepatitis (AIH) and primary sclerosing cholangitis (PSC). The two conditions have chronicity, liver inflammation, and a positive autoimmune serology in common; they differ in terms of gender distribution and bile duct damage.
Vergani, Diego, Mieli-Vergani, Giorgina
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2019
Addressing the factors that influence worker health is in the interest of employees and organisations, and has implication for national productivity. In particular, practices that protect employee mental health and promote wellbeing are important to prevent psychological harm that can be attributed to workplace factors, and improve organisational ...
Maureen F. Dollard, Tessa Bailey
openaire +1 more source
Addressing the factors that influence worker health is in the interest of employees and organisations, and has implication for national productivity. In particular, practices that protect employee mental health and promote wellbeing are important to prevent psychological harm that can be attributed to workplace factors, and improve organisational ...
Maureen F. Dollard, Tessa Bailey
openaire +1 more source
2019
The aim of this chapter is to introduce the PSC-4 short tool created as a parsimonious measure of PSC, with the same domain coverage as the PSC-12 (canvassing the four domains of PSC), that could be used in research and practice with only four items.
openaire +1 more source
The aim of this chapter is to introduce the PSC-4 short tool created as a parsimonious measure of PSC, with the same domain coverage as the PSC-12 (canvassing the four domains of PSC), that could be used in research and practice with only four items.
openaire +1 more source