Results 1 to 10 of about 145,081 (341)
PSD-95 Protects Synapses From β-Amyloid [PDF]
Cell Reports, 2021 SUMMARY Beta-amyloid (Aβ) depresses excitatory synapses by a poorly understood mechanism requiring NMDA receptor (NMDAR) function. Here, we show that increased PSD-95, a major synaptic scaffolding molecule, blocks the effects of Aβ on synapses.
Kim Dore +2 more
exaly +3 more sources
α-Actinin Anchors PSD-95 at Postsynaptic Sites [PDF]
Neuron, 2018 SUMMARY Despite the central role PSD-95 plays in anchoring postsynaptic AMPARs, how PSD-95 itself is tethered to postsynaptic sites is not well understood.
Durga P Mohapatra +2 more
exaly +3 more sources
Sparse PSD approximation of the PSD cone [PDF]
Mathematical Programming, 2020 While semidefinite programming (SDP) problems are polynomially solvable in theory, it is often difficult to solve large SDP instances in practice. One technique to address this issue is to relax the global positive-semidefiniteness (PSD) constraint and ...
G. Blekherman +3 more
semanticscholar +4 more sources
PSD-95 Binding Dynamically Regulates NLGN1 Trafficking and Function
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance PSD-95 is a key scaffolding protein that is localized to the postsynaptic density of excitatory synapses where it regulates a wide variety of receptors, channels, and signaling molecules.
Wei Lu, Katherine Roche, Saurabh Pandey
exaly +2 more sources
Cell Reports, 2017 The PSD-95/SAPAP/Shank complex functions as the major scaffold in orchestrating the formation and plasticity of the post-synaptic densities (PSDs). We previously demonstrated that the exquisitely specific SAPAP/Shank interaction is critical for Shank ...
Jinwei Zhu, Mingjie Zhang, Youming Lu
exaly +2 more sources
Ageing Research Reviews, 2014 The postsynaptic density protein PSD-95 is a major element of synapses. PSD-95 is involved in aging, Alzheimer's disease (AD) and numerous psychiatric disorders.
Armand Savioz
exaly +2 more sources
Min(Max-PSD) and Max(Min-PSD) as lifetime distributions in Network’s Reliability
Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2022 In our paper we describe the corresponding dynamic mathematical models to perform a comparative analysis of the reliability of two types of networks: serial-parallel and parallel-serial when the number of subnetworks is constant and the numbers of units ...
Leahu Alexei +3 more
doaj +2 more sources
Bad projections of the PSD cone [PDF]
Collectanea Mathematica, 2021 AbstractThe image of the cone of positive semidefinite matrices under a linear map is a convex cone. Pataki characterized the set of linear maps for which that image is not closed. The Zariski closure of this set is a hypersurface in the Grassmannian. Its components are the coisotropic hypersurfaces of symmetric determinantal varieties.
Yuhan Jiang, Bernd Sturmfels
openaire +4 more sources
“Protect, test, vaccinate”: dealing with Covid-19 in outpatient psychiatric care
European Psychiatry, 2022 Introduction Curbing the spread of the coronavirus and stabilizing the overall psychosocial situation requires compliance with preventive measures: “Protect, test, vaccinate”.
G. Psota, S. Schuett, B. Vyssoki
doaj +1 more source
Effect of an Educational Intervention on Dietary Diversity Practices among Public School Students
Journal of Nepal Health Research Council, 2021 Background: Poor dietary diversity leading to malnutrition among children and adolescents is a serious public health problem in Nepal. Though nutrition education intervention has been effective in changing the dietary intake habits of individuals in ...
Binod Kumar Aryal +3 more
doaj +1 more source