Results 161 to 170 of about 81,829 (309)

The regulatory frameworks surrounding CRISPR‐edited papaya and their impact on international commerce

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract The papaya tree (Carica papaya L.), native to the Americas, is cultivated in tropical regions and holds substantial economic importance, with an estimated export volume of 365 000 t in 2023. However, diseases caused by viruses, fungi, bacteria, and nematodes can lead to severe losses.
Luíza Favaratto   +7 more
wiley   +1 more source

Clinical Efficacy and Safety of Topical Roflumilast in Psoriasis: An Updated Systematic Review and Meta‐Analysis of Randomized Controlled Trials

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Traditional first‐line topical treatments for plaque psoriasis, particularly corticosteroids and vitamin D analogs, frequently have only limited efficacy for long‐term use, and present difficulties with safety and adherence. Objectives In this systematic review and meta‐analysis of randomized controlled trials (RCTs), we assessed ...
Aimal A. Khattak   +11 more
wiley   +1 more source

Enriched Environment Enhances Motor Function in Mice With Cerebral Infarction by Promoting mTOR‐Dependent Autophagy in the Contralateral Dentate Nucleus

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Although environmental enrichment (EE) promotes post‐stroke motor recovery, the mechanisms underlying its regulation of cerebellar dentate nucleus (DN) plasticity remain unclear; this study therefore investigated how EE coordinates autophagy, mitochondrial homeostasis, and synaptic remodeling in the contralateral DN to facilitate functional ...
Chuan‐Jie Wang   +3 more
wiley   +1 more source

Timing of ACL injuries during elite male football (soccer) matches—Impact of player position, substitutes, contact mechanisms, possession status and situational pattern: An analysis of 369 ACL injuries

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To document the timing of anterior cruciate ligament (ACL) injuries according to match minute and effective minutes played during football matches, considering player position, substitutions, contact mechanism, possession status and situational pattern.
Matthew Buckthorpe   +4 more
wiley   +1 more source

Multimode Phonon Lasing via Self‐Induced Optical Coherent Pumping

open access: yesLaser &Photonics Reviews, EarlyView.
A silicon optomechanical nanobeam generates self‐sustained phonon lasing in multiple competing mechanical modes via self‐pulsing, an intrinsic optical modulation arising from cavity nonlinearity. This self‐organized mechanism enables robust multi‐frequency operation spanning periodic, quasi‐periodic, and chaotic regimes without external modulation. The
David Alonso Tomás   +5 more
wiley   +1 more source

Deterministic Fiber‐Optic Spectral Engineering Enables Three‐Color Multiplexed Two‐Photon Microscopy

open access: yesLaser &Photonics Reviews, EarlyView.
A simulation‐guided spectral‐engineering framework maps the nonlinear parameter space of a fiber laser platform to identify balanced three‐band excitation states. The resulting 960, 1080, and 1175 nm femtosecond pulses deliver nJ‐level energies for low‐cross‐talk chromatically multiplexed two‐photon microscopy.
Marvin Edelmann   +5 more
wiley   +1 more source

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