Results 171 to 180 of about 1,425,533 (307)

SpatialESD: Spatial Ensemble Domain Detection in Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
ABSTRACT Spatial transcriptomics (ST) measures gene expression while preserving spatial context within tissues. One of the key tasks in ST analysis is spatial domain detection, which remains challenging due to the complex structure of ST data and the varying performance of individual clustering methods. To address this, we propose SpatialESD, a Spatial
Hongyan Cao   +11 more
wiley   +1 more source

Estimating Life—Cycle Parameters from Consumption Behavior at Retirement” [PDF]

open access: yes
Using pseudo-panel data, we estimate the structural parameters of a life—cycle consumption model with discrete labor supply choice. A focus of our analysis is the abrupt drop in consumption upon retirement for a typical household.
Dan Silverman, John Laitner
core  

Electron‐Phonon Interactions Facilitating Large Polaron‐Related Charge‐Carrier Dynamics for Efficient Perovskite Nanocrystal Solar Cells

open access: yesAdvanced Science, EarlyView.
We developed a custom‐synthesized ligand, 2‐thiophenepropenammonium iodide, to exchange the native ligands capped on inorganic perovskite nanocrystals (NCs), and identified that the significantly decreased strength of electron‐phonon interaction benefited the charge‐carrier dynamics in their assembled films.
Wei Guo   +12 more
wiley   +1 more source

Pseudo-Panel Data Estimation of Japanese Tobacco Consumption

open access: yesJournal of Rural Problems, 2010
Phocenah Nyatanga, Toshinobu Matsuda
openaire   +2 more sources

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

open access: yesAdvanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao   +12 more
wiley   +1 more source

EDTA‐Functionalized Nanoscale Metal–Organic Framework for Onco‐Cardiology via Radiochemotherapy Synergy and Spatiotemporally Matched Iron Chelation

open access: yesAdvanced Science, EarlyView.
Doxorubicin (DOX)‐induced cardiotoxicity is a major limitation to its broader clinical application, while cardioprotective interventions often risk reducing the anticancer efficacy of DOX. To address these challenges, this work constructs an EDTA‐functionalized metal–organic framework that enhances tumor therapy and provides efficient cardioprotection ...
Daojing Yuan   +8 more
wiley   +1 more source

Atomic Defects in Layered Transition Metal Dichalcogenides for Sustainable Energy Storage and the Intelligent Trends in Data Analytics

open access: yesAdvanced Science, EarlyView.
This review comprehensively summarizes the atomic defects in TMDs for their applications in sustainable energy storage devices, along with the latest progress in ML methodologies for high‐throughput TEM data analysis, offering insights on how ML‐empowered microscopy facilitates bridging structure–property correlation and inspires knowledge for precise ...
Zheng Luo   +6 more
wiley   +1 more source

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